Placental Infections.

Clin Obstet Gynecol

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, NYU Grossman Long Island School of Medicine, New York University Langone Hospital Long Island.

Published: December 2024

AI Article Synopsis

  • The review analyzes how different infections in pregnant women affect their health, the baby’s development, and the placenta.
  • It discusses various types of infections (bacterial, viral, parasitic), their transmission, symptoms, and how they can be identified through placental examination.
  • The importance of early diagnosis and treatment is highlighted, as many infections can show no symptoms, and the placenta's role in protecting against these infections is also explored.

Article Abstract

This comprehensive review examines the effects of various infections on pregnancy, focusing on maternal symptoms, fetal outcomes, diagnostic methods, and placental pathology. The paper covers bacterial, viral, and parasitic infections, their mechanisms of transmission, clinical presentations, and histopathologic findings in the placenta. It emphasizes the importance of early detection and intervention, highlighting the challenges in diagnosis due to often asymptomatic presentations. The review also discusses the placenta's role as a protective barrier and its immune defense mechanisms against pathogens. Overall, this paper serves as a comprehensive resource for understanding the complex interplay between maternal infections, placental pathology, and fetal outcomes.

Download full-text PDF

Source
http://dx.doi.org/10.1097/GRF.0000000000000919DOI Listing

Publication Analysis

Top Keywords

fetal outcomes
8
placental pathology
8
placental infections
4
infections comprehensive
4
comprehensive review
4
review examines
4
examines effects
4
effects infections
4
infections pregnancy
4
pregnancy focusing
4

Similar Publications

Nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy, is a rare inherited neurometabolic disorder caused by a deficiency in the glycine cleavage enzyme system (GCS), leading to the pathological accumulation of glycine in blood and cerebrospinal fluid (CSF). This case report details a neonate presenting with central apnea, profound hypotonia, and refractory seizures, alongside prenatal findings of polyhydramnios and hiccup-like fetal movements, all strongly suggestive of severe NKH. Diagnostic evaluation confirmed markedly elevated glycine levels in serum and CSF, with a CSF-to-plasma glycine ratio exceeding 0.

View Article and Find Full Text PDF

Acute severe ulcerative colitis (ASUC) in pregnancy poses a clinical challenge with significant risk to both mother and fetus. Anti-TNF alpha therapy is known to be safe in pregnancy, however, data surrounding outcomes in ASUC is limited. In this report, we present the case of a pregnant patient of 10 weeks' gestation with ASUC successfully managed with intensified and accelerated infliximab therapy for a total dose of 35 mg/kg during a single admission.

View Article and Find Full Text PDF

Optimising Luteinising Hormone Levels on Trigger Day for Improved Ovarian Response and Pregnancy Outcomes in Gonadotropin-Releasing Hormone Antagonist Protocols: A Retrospective Cohort Study.

BJOG

January 2025

Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology, Guangdong-Hong Kong-Macao Greater Bay Area Higher Education Joint Laboratory of Maternal-Fetal Medicine, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

Objective: To determine the optimal luteinising hormone (LH) level on the trigger day and its impact on pregnancy outcomes in gonadotropin-releasing hormone (GnRH) antagonist protocols using a data-driven approach.

Design: Retrospective cohort study.

Setting: Third Affiliated Hospital of Guangzhou Medical University.

View Article and Find Full Text PDF

Misreading Medicine: Statutory Prohibitions of Abortion for Disability.

J Med Humanit

January 2025

S.J. Quinney College of Law, University of Utah, Salt Lake City, UT, USA.

Abortion prohibitions in some states include carve-outs based on the medical condition of either the mother or the fetus. These carve-outs, however, may be couched in limiting language structured by legislators rather than in language understandable in the context of medical care. In circumstances where legislative bodies fail to adequately incorporate medical professionals in the drafting of medical laws, the resulting vagueness or ambiguity may lead to a lack of utility or viability.

View Article and Find Full Text PDF

Purpose: This study aimed to compare the treatment outcomes of the closure methods between pre and post-eras of bedside wound retractor silo placement technique (BSC).

Methods: This retrospective cohort study included infants diagnosed with gastroschisis from 2006-2013, pre-BSC era, and from 2014-2021, BSC era. Infants who had fetal anomalies did not survive before receiving treatment and were treated with the delayed closure method were excluded.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!