Germ cell development: Anchoring and pulling forces shape germline cyst construction.

Curr Biol

Department of Developmental Biology and Cancer Research, The Hebrew University of Jerusalem, Faculty of Medicine, Ein-Kerem Campus, Jerusalem 9112102, Israel; Institute for Medical Research - Israel-Canada (IMRIC), Ein-Kerem Campus, Jerusalem 9112102, Israel. Electronic address:

Published: December 2024

A new study reports a 'tug-of-war' mechanism in mouse germline cyst formation, where cell motility and intercellular bridges balance fragmentation and stabilization of the cyst. These dynamic and opposing forces that anchor and pull cells apart shape cyst construction, advancing our understanding of mammalian oogenesis and reproduction.

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Source
http://dx.doi.org/10.1016/j.cub.2024.10.072DOI Listing

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