Aim of the study was to assess the use of pharmacological therapies provided in Nursing Homes and Protected Residences of the Umbria Region, with reference to central nervous system medications. In 2022, 200 ddd (defined daily doses) per 100 bed-days were administered in Umbria's long term care facilities, representing a 6.2% decrease compared to the previous year. Dermatological drugs had the highest consumption (35 ddd), followed by antihypertensives (26.5 ddd) and laxatives (15.6 ddd). Categories with the largest increases included antianemic preparations (+136%) and non-systemic antibiotics (+21%). Among Cns drugs, benzodiazepines and antipsychotics increased by 18% and 0.5 ddd respectively, while antidepressants decreased by 17.1%. In the setting of long-term care, a person-centered therapeutic approach should be considered to ensure the well-being of patients.
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