This comment discusses a recent research paper on the classification of saliva samples with SERS by Borsa et al. The authors suggested utilizing PCA-LDA to detect oral cancer and claimed to achieve an accuracy of up to 77%. Despite the high prediction capability of the proposed approach, the demonstrated findings could be treated as unclear due to possible overestimation of the proposed classification models. Data should be provided for both the training and the validation sets to make sure that there were no repeated data from the same sample in either set. Moreover, the authors proposed to measure opiorphin in saliva with SERS as a potential biomarker of oral cancer. However, opiorphin in saliva is contained in ng/mL concentrations, and the proposed technique is most likely not capable of recording the real concentration of opiorphin.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11641564 | PMC |
| http://dx.doi.org/10.3390/ijms252313030 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Chapter 2: PRIMARY HYPERPARATHYROIDISM: DIAGNOSIS.
Ann Endocrinol (Paris)
January 2025
University of Brest, CHU Brest, UMR1304 GETBO, 29200 Brest, France; Endocrinology and Diabetology Department, CHU Brest, 29200 Brest, France.
Primary hyperparathyroidism is now predominantly an asymptomatic pathology, as blood calcium assay has become systematic. Diagnosis therefore requires screening for target organ damage when this is not already indicative of primary hyperparathyroidism.Classical clinical manifestations include bone, kidney and muscle signs, and are characterized by reversibility after parathyroid surgery.
View Article and Find Full Text PDFPreparation of Anterolateral Thigh Flap from Polio-Affected Lower Limb: A Safe Surgical Option that Preserves Patient's Motor Function.
J Stomatol Oral Maxillofac Surg
January 2025
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, 430079, Wuhan, P.R. China; Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Wuhan University, 430079, Wuhan, P.R. China. Electronic address:
The anterolateral thigh (ALT) flap is a commonly used donor site for free tissue transfer, especially in head and neck reconstructions. The flap's success is primarily determined by the quality and quantity of its perforating vessels, which is why clinicians typically prefer harvesting from a healthy leg with intact vascular anatomy. Poliomyelitis typically causes unilateral lower limb paralysis, resulting in muscle atrophy and deformities.
View Article and Find Full Text PDFReadiness for hospital discharge and associated factors in patients with oral cancer: A cross-sectional study.
Eur J Oncol Nurs
January 2025
State Key Laboratory of Oral Diseases & National Center for Stomatology &National Clinical Research Center for Oral Diseases & Department of Orthognathic and TMJ Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China. Electronic address:
Purpose: To evaluate the current status of discharge readiness among postoperative oral cancer patients and identify the primary associated factors.
Methods: Information from 713 oral cancer patients was collected using questionnaire surveys. One-way ANOVA or t-tests were employed to compare differences in discharge readiness across various demographic characteristics.
Development and Evaluation of an Automated Multimodal Mobile Detection of Oral Cancer (mDOC) Imaging System to Aid in Risk-based Management of Oral Mucosal Lesions.
Cancer Prev Res (Phila)
January 2025
Rice University, Houston, Texas, United States.
Oral cancer is a major global health problem. It is commonly diagnosed at an advanced stage although often preceded by clinically visible oral mucosal lesions, termed oral potentially malignant disorders associated with an increased risk for oral cancer development. There is an unmet clinical need for effective screening tools to assist front-line healthcare providers to determine which patients should be referred to an oral cancer specialist for evaluation.
View Article and Find Full Text PDFTwo Head and Neck Cancers in an Adult With Intellectual Disability and Rett Syndrome: A Case Report.
Spec Care Dentist
January 2025
Department of Head & Neck Surgery, Singapore General Hospital, Singapore, Republic of Singapore.
The cases of head and neck cancer among persons with intellectual disability (PWID) are infrequently reported and therefore poorly understood. PWID often face increased barriers of access to healthcare, which can be further compounded when faced with a cancer diagnosis. This report presents the case of a 34-year-old Chinese female patient with Rett syndrome and intellectual disability, presenting with two primary cancers of the tongue and the trachea.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!