Interplay between lncRNAs and microrNAs in hypertension.

Hypertens Res

Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Tamil Nadu, India.

Published: December 2024

The interplay between long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) in regulating hypertension modulate gene expression through different mechanisms, influencing key physiological and pathological processes. Specifically, interactions between lncRNAs and miRNAs affect various molecular pathways, including the renin-angiotensin-aldosterone system, which plays a critical role in blood pressure regulation. The lncRNA MALAT1 is particularly noted for its role in inflammation and oxidative stress regulation, suggesting potential targets for hypertension treatment and diagnostics. Interplay between lncRNAs and MicroRNAs in Hypertension.

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Source
http://dx.doi.org/10.1038/s41440-024-01888-0DOI Listing

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