AI Article Synopsis
- - This study investigated how life-space activities relate to the development of dementia in older adults, involving 2,740 participants with an average age of 74.4 years.
- - Researchers used the Active Mobility Index (AMI) to measure life-space activities and tracked dementia cases over an average follow-up of about 54 months, finding that 11.9% of participants developed dementia.
- - Results indicated that higher AMI scores correlated with a lower risk of dementia, with both physical and social activity levels being significant factors in dementia risk.
Article Abstract
Objectives: This study examined the association between life-space activities and incident dementia among older adults.
Study Design: A prospective study.
Setting And Participants: This study included 2740 older adults (mean age 74.4 years; SD ± 6.2 years; range 65-99 years; 58.8% women).
Methods: Life-space activities were assessed using the Active Mobility Index (AMI). Incident dementia was determined using medical insurance data and long-term care insurance data (mean follow-up, 53.7 months).
Results: During the follow-up period, 326 participants (11.9%) had incident dementia. Participants were classified into 3 groups based on AMI score tertiles: tertile 1, ≤52; tertile 2, 53-77; and tertile 3, ≥78. The Cox proportional hazards model was used to examine the association between AMI scores and incident dementia. Individuals with higher scores had lower hazard ratios (HRs) (tertile 1: reference; tertile 2: adjusted HR, 0.76, 95% CI, 0.59-0.97, P = .027; tertile 3: adjusted HR, 0.49, 95% CI, 0.36-0.68, P < .001; P for trend: <.001). Both the physical and social AMI sub-scores were associated with dementia (P for trend: <.001).
Conclusions And Implications: Restricted life-space activity, as assessed using the AMI, was associated with the risk of dementia. In addition, both the physical and social sub-scores were associated with dementia.
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| http://dx.doi.org/10.1016/j.jamda.2024.105416 | DOI Listing |
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