Electrical Stimulation Therapy - Dedicated to the Perfect Plastic Repair.

Adv Sci (Weinh)

Department of Plastic Surgery, State Key Laboratory of Trauma and Chemical Poisoning, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.

Published: December 2024

AI Article Synopsis

  • * The review covers different sources of electrical stimulation and the best electrode materials suited for clinical applications, discussing their biological impacts on cells and tissues.
  • * Future developments will focus on improving equipment performance and meeting clinical needs, emphasizing the importance of safety, feasibility, and cost-effectiveness in these technologies.

Article Abstract

Tissue repair and reconstruction are a clinical difficulty. Bioelectricity has been identified as a critical factor in supporting tissue and cell viability during the repair process, presenting substantial potential for clinical application. This review delves into various sources of electrical stimulation and identifies appropriate electrode materials for clinical use. It also highlights the biological mechanisms of electrical stimulation at both the subcellular and cellular levels, elucidating how these interactions facilitate the repair and regeneration processes across different organs. Moreover, specific electrode materials and stimulation sources are outlined, detailing their impact on cellular activity. The future development trends are projected from two perspectives: the optimization of equipment performance and the fulfillment of clinical demands, focusing on the feasibility, safety, and cost-effectiveness of technologies.

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Source
http://dx.doi.org/10.1002/advs.202409884DOI Listing

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