Purpose: This study aimed to examine the effect of elective neck dissection (END) on the prognosis of patients with cT3/T4N0 maxillary sinus squamous cell carcinoma (MSSCC).
Methods: Data were obtained from the SEER database. Patients with cT3/T4a/T4bN0 MSSCC were included in the study and divided into two groups: those who received END treatment and those who did not. Differences between the two groups were assessed using propensity score matching. Cox regression was used to screen patients for independent risk factors. The effect of END on cancer-specific survival (CSS) and overall survival (OS) was explored, and subgroup analyses were performed.
Results: A total of 327 patients with cT3/T4N0 MSSCC were enrolled. After propensity score matching (PSM), patients treated with END showed significant improvement in overall survival (OS) and cancer-specific survival (CSS) compared with those who did not receive END (P < 0.05). In subgroup analyses, the hazard ratio was 0.729 (95% confidence interval: 0.549-0.967), indicating a favourable prognosis for patients receiving END. Certain subgroups of patients benefited significantly from END. These subgroups included patients older than 65 years, Caucasian, male, not receiving radiotherapy, stage T3, grade II and MSSCC with a tumour size of 3-5 cm.
Conclusion: END improves survival time and survival outcomes in patients with cT3/T4a/T4bN0 MSSCC, especially in cT3 patients.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00405-024-09146-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Cervicothoracic Emphysema After Nasotracheal Intubation Attempt: A Life-Threatening Complication-A Case Report.
A A Pract
January 2025
From the Departments of Anesthesiology.
Nasotracheal intubation is a commonly used technique in elective oral and pharyngeal surgeries. This case report details an incident involving a young adult patient in which an attempt at nasotracheal intubation resulted in a life-threatening cervicofacial and thoracic emphysema. Although complications associated with nasotracheal intubation are rare, their potential severity necessitates a comprehensive preprocedural discussion and risk assessment with the surgical team to confirm its appropriate indication for each individual patient.
View Article and Find Full Text PDFMode of birth in nulliparous term singleton pregnancies in vertex presentation before and after implementation of an evidence-based intervention: quality-improvement study.
J Matern Fetal Neonatal Med
December 2025
2nd Department of Gynecology and Obstetrics, University Hospital Bratislava and Comenius University, Bratislava, Slovakia.
Purpose: The main objective of this study was to assess the impact of a composite quality improvement intervention on mode of birth in nullipara term singleton vertex (NTSVs).
Material And Methods: This was an ambidirectional study following the implementation of the intervention to reduce cesarean section rate in NSTV by comparing two birth cohorts, pre-composite quality improvement intervention cohort (January 2013-December 2015) and post-composite quality improvement intervention cohort (January 2018-December 2020).
Results: In the studied periods, there was a total of 7713 NTSV births.
Treatment Decision-Making Among Chinese Americans With Chronic Rhinosinusitis.
Laryngoscope
January 2025
Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, California, U.S.A.
Objective: There has been limited research on the influence of race and ethnicity on treatment decision-making for chronic rhinosinusitis (CRS). This prospective study aims to investigate potential factors linked to treatment modality choice among patients with medically refractory CRS, distinguishing between Chinese American and non-Chinese American patients.
Methods: CRS patients with persistent symptoms despite prior medical treatment were prospectively enrolled.
Comparison of Direct Laryngoscopy With McCoy Blade and BPL Video Laryngoscopy for Intubation in Patients Undergoing Elective Cervical Spine Surgery.
Cureus
November 2024
Anesthesiology and Critical Care, Uttar Pradesh University of Medical Sciences, Etawah, IND.
Background: For patients having cervical spine instability, stabilization of the neck is crucial to prevent further damage to the spinal cord, which can make laryngoscopy challenging. Specialized tools like McCoy blade direct laryngoscope (Surgitech, India) and BPL video laryngoscope (BPL Medical Technologies Pvt. Ltd.
View Article and Find Full Text PDF"Robotic elective neck dissection in early-stage tongue cancer: A critical appraisal of oncologic and cosmetic outcomes".
Eur J Surg Oncol
December 2024
Department of Head and Neck Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. Electronic address:
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!