Radiation therapy is used in the treatment of various cancers, and advancements in irradiation techniques have further expanded its applicability. For radiation oncologists, predicting adverse events remains a critical challenge, even with these technological advancements. Although numerous studies have been conducted to predict individual radiosensitivity, no biomarkers have been clinically applied thus far. This review focuses on γ-H2AX foci and chromosomal aberrations, providing an overview of their association with normal tissue toxicities.
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| http://dx.doi.org/10.1093/jrr/rrae081 | DOI Listing |
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