AI Article Synopsis
- Four new compounds called crydensiones A‒D (1‒4) were discovered in the twigs and leaves of the plant Cryptocarya densiflora.
- Their structures were identified using advanced methods like spectroscopy and quantum chemical calculations, including electronic circular dichroism (ECD) and nuclear magnetic resonance (NMR).
- None of the isolated compounds showed significant cytotoxic effects against various cancer cell lines (colon, lung, and breast) in the tests conducted.
Article Abstract
Four previously undescribed arylalkenyl α-pyrones, designated as crydensiones A‒D (1‒4), were isolated from the twigs and leaves of Cryptocarya densiflora. Their structures were determined through comprehensive spectroscopic analyses together with quantum chemical calculations of electronic circular dichroism (ECD) and nuclear magnetic resonance (NMR) data. All isolates were assessed for cytotoxicity against HCT-116 (colon), A549 (lung), and MDA-MB-231 (breast) cancer cell lines; however, none demonstrated significant activity.
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| http://dx.doi.org/10.1002/cbdv.202403120 | DOI Listing |
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