Introduction Radiotherapy is a cornerstone in cancer treatment as a part of multidisciplinary team management. The field has evolved significantly over the past two decades due to technological advancement. To meet the increased need for manpower in the field, the radiation oncology residency program was first established in Saudi Arabia back in 2019. Purpose We sought to survey the trainees' current experience across the country to establish a baseline for the different training aspects and to tackle any challenges that might go unnoticed. Materials and methods This is a cross-sectional survey-based study that targeted all residents enrolled in the Saudi radiation oncology training program, except the first-year residents. The trainees received an anonymous online questionnaire aiming to assess their involvement in every aspect of the daily workflow. Results A total of 13 eligible radiation oncology residents in Saudi Arabia were included. Eleven residents completed the survey with a national response rate of 85%. Nine (82%) of the trainees reported that they review the contours and the treatment plans with their attendings in person and this method of review is the preferred one over the hybrid method as it provides better teaching quality, interactivity, and prompt feedback. Most respondents do not review offline (7, 64%) or online (6, 55%) cone beam computed tomography (CBCT) scans with their attendings, citing the limited involvement in the approval process. Conclusion This study uncovered a need for better resident integration into day-to-day clinical workflow, particularly in CBCT review and approval. Addressing the current concerns will enhance the educational experience and future practice. Acknowledging the limitations of our study, we observed that certain deficiencies in core competencies reported in long-established North American programs align with our findings. This underscores the need for addressing these gaps through continuous and unbiased evaluations of radiation oncology residency training programs to enhance the educational experience and ensure high-quality preparation for independent practice.
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http://dx.doi.org/10.7759/cureus.73754 | DOI Listing |
Neurol Sci
December 2024
Department of Neurology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ann Surg Oncol
December 2024
Division of Breast Surgery, Department of Surgery, Linkou Chang Gung Memorial Hospital, Taoyüan, Taiwan, R.O.C..
Background: We investigated the perioperative outcome and oncologic safety of performing nipple-sparing mastectomy (NSM) through a single axillary incision (NSM-SAI) compared with performing NSM through a conventional incision (NSM-C).
Methods: We retrospectively reviewed 725 patients who underwent NSM for breast cancer between January 2010 and December 2023; 333 patients who underwent NSM with immediate reconstruction (IR) were enrolled. Surgical outcomes and oncologic outcomes of NSM-C (n = 184), NSM performed through SAI with a freehand approach (NSM-SAI-F; n = 92), and with an endoscopic approach (NSM-SAI-E; n = 57) were demonstrated.
Biomaterials
December 2024
Institute of Precision Medicine, Peking University Shenzhen Hospital, 518036, Shenzhen, China. Electronic address:
Radiotherapy, employing high-energy rays to precisely target and eradicate tumor cells, plays a pivotal role in the treatment of various malignancies. Despite its therapeutic potential, the effectiveness of radiotherapy is hindered by the tumor's inherent low radiosensitivity and the immunosuppressive microenvironment. Here we present an innovative approach that integrates peroxynitrite (ONOO)-mediated radiosensitization with the tumor-associated neutrophils (TANs) polarization for the reversal of immunosuppressive tumor microenvironment (TME), greatly amplifying the potency of radiotherapy.
View Article and Find Full Text PDFTransl Oncol
December 2024
Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China; Department of Shandong Provincial Key Laboratory of Precision Oncology, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China. Electronic address:
Objective: To evaluate the efficacy and safety of the continuing immunotherapy as subsequent therapy in extensive-stage small cell lung cancer (ES-SCLC) patients who have progressed after initial immunotherapy.
Methods: A retrospective analysis was conducted on patients with ES-SCLC who experienced disease progression after receiving programmed cell death ligand 1 (PD-L1) inhibitors combined with standard chemotherapy as first-line treatment at three sites in China. Patients were divided into two groups according to whether to continue second-line immunotherapy.
Neoplasia
December 2024
AMES, Centro Polidiagnostico Strumentale srl, Via Padre Carmine Fico 24, Casalnuovo Di Napoli 80013, Italy.
Background: Oligo-metastatic disease (OMD) in colon cancer patients exhibits distinct clinical behavior compared to poly-metastatic disease (PMD), with a more responsive and indolent course. This study aims to identify clinical and biological factors uniquely associated with oligo-metastatic behavior.
Methods: Metastatic colon cancer patients from an academic center underwent genetic characterization.
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