AI Article Synopsis
- * Researchers analyzed data from 437 patients to identify risk factors for PAS using logistic regression, creating a predictive model validated by additional patient data, showing an AUC of 0.821.
- * Key risk factors identified included neutrophil-to-lymphocyte ratio, cesarean section timing, and specific types of placenta previa; the model offers potential for early diagnosis and management of PAS in affected women.
Article Abstract
Background: Placenta previa, occurring when the placenta covers the cervical opening after 28 weeks, can lead to severe postpartum bleeding, especially when coupled with placenta accreta spectrum (PAS), posing risks of organ damage and necessitating hysterectomy. Accurate preoperative diagnosis of PAS in women with placenta previa is crucial to reduce adverse outcomes.
Objectives: This study aimed to develop a risk prediction model for PAS in women with placenta previa.
Material And Methods: A total of 437 patients with placenta previa, delivering babies between January 2012 and December 2018, were included. Data collected encompassed clinical records, neutrophil-to-lymphocyte ratio (NLR) and sonographic findings. Utilizing univariate and multivariate logistic regression analyses, the study identified key factors correlated with PAS in expectant mothers with placenta previa. A risk prediction model was formulated and evaluated through receiver operating characteristic (ROC) analysis. External validation was performed using additional patients diagnosed with placenta previa.
Results: Independent risk factors for PAS in placenta previa included NLR, timing of cesarean section and miscarriage, placenta previa type, presence of placental lacunae, and uterovesical hypervascularity. The predictive model was established using specific coefficients. The ROC curve indicated an area under the curve (AUC) of 0.821, with a sensitivity of 80.6% and specificity of 68.9%. External validation demonstrated a diagnosis coincidence rate of 75%, and the model exhibited good calibration according to the Hosmer-Lemeshow test (p = 0.3742, >0.05).
Conclusions: The developed model showed effective potential in predicting PAS among women with placenta previa. Its application could significantly contribute to the early detection and subsequent management of PAS.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.17219/acem/191828 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Takayasu's arteritis in pregnancy: A case report and literature review.
Int J Gynaecol Obstet
December 2024
Department of Obstetrics and Gynaecology, Kathmandu Medical College Public Limited, Kathmandu, Nepal.
Takayasu's arteritis (TA) is a rare, chronic inflammatory disease of unknown cause, primarily affecting young women in their reproductive years. It can result in the narrowing and occlusion of arteries and the formation of aneurysms in arteries, especially those related to the aorta, creating significant risks during pregnancy. Women with TA are more susceptible to cardiovascular complications, including hypertension and heart failure, which can negatively affect both maternal and fetal health.
View Article and Find Full Text PDFMaternal Morbidity and Medically Assisted Reproduction Treatment Types.
Obstet Gynecol
December 2024
Centre for Longitudinal Studies, Social Research Institute, University College London, London, United Kingdom; Population Science, Huntsman Cancer Institute, the Department of Family and Consumer Studies, the Department of Obstetrics and Gynecology, and the Spencer Fox Eccles School of Medicine, University of Utah, Salt Lake City; Max Planck Institute for Demographic Research, Rostock, Germany; the Helsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland; and the Max Planck - University of Helsinki Center for Social Inequalities in Population Health, Rostock, Germany and Helsinki, Finland.
Objective: To compare odds of maternal morbidity by mode of becoming pregnant and type of medically assisted reproduction treatments: fertility-enhancing drugs, intrauterine insemination (IUI), and assisted reproductive technology (ART) with autologous or donor oocytes.
Methods: Birth certificates were used to study maternal morbidity among the birthing population in Utah between 2009 and 2017 (N=469,919 deliveries); 22,543 pregnancies occurred through medically assisted reproduction (4.8%).
Association between obesity in women with multiple gestations and adverse obstetric outcomes: a study of an American population database with over 136,000 unique deliveries.
Arch Gynecol Obstet
December 2024
Obstetrics and Gynecology, McGill University Health Centre, Montreal, Canada.
Purpose: The purpose of this study is to compare obese and non-obese women with multiple pregnancies to determine the effects on pregnancy, delivery, and neonatal outcomes.
Methods: We conducted a retrospective population-based study utilizing data collected between 2004 and 2014 inclusively, from the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample. A total of 137,303 multiple pregnancies were analyzed; 130,542 (95%) were non-obese, while 6761 (5%) were obese.
Abnormal microRNA expression profile at early stages of gestation in pregnancies destined to develop placenta previa.
Front Med (Lausanne)
December 2024
Institute for the Care of the Mother and Child, Third Faculty of Medicine, Charles University, Prague, Czechia.
Background: Placenta previa is the abnormal implantation of the placenta into the lower segment of the uterus, is associated with adverse maternal and fetal outcomes such as placenta accreta spectrum disorders, antepartum and postpartum hemorrhage, fetal growth restriction, prematurity, stillbirth and neonatal death, thrombophlebitis, and septicemia. The aim of the study was to assess retrospectively how the later onset of placenta previa affects the microRNA expression profile in the whole peripheral blood during the first trimester of gestation.
Methods: Regarding the occurrence of the association between aberrant microRNA expression profiles at early stages of gestation and later onset of various pregnancy-related complications, we selected for the study pregnancies developing placenta previa as the only pregnancy-related disorder.
Risk Factors of Marginal Cord Insertion in Singleton Pregnancies: A Systematic Review and Meta-Analysis.
J Clin Med
December 2024
Third Department of Obstetrics and Gynecology, Faculty of Health Sciences, School of Medicine, Aristotle University of Thessaloniki, Agiou Dimitriou, 54124 Thessaloniki, Greece.
Marginal cord insertion (MCI) is increasingly recognized as a pathological variation that necessitates early diagnosis. Identifying the risk factors associated with MCI is essential for improving prenatal screening and optimizing management strategies. Our meta-analysis systematically and quantitatively synthesizes the current evidence on various potential risk factors for MCI.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!