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[Surgical treatment for intractable constipation: selection of procedure and perioperative management].
Zhonghua Wei Chang Wai Ke Za Zhi
December 2024
Department of General Surgery, General Hospital of Eastern Theater Command, PLA, Nanjing 210002, China.
When chronic constipation develops to the stage of intractable constipation, the symptoms of constipation in patients are severe and persistent, and drug treatment is often ineffective, so surgical treatment is often considered. The clinical manifestations of patients with intractable constipation are variable, and the underlying pathophysiological changes involve various abnormal and dysfunctional anatomical structure of colorectal and pelvic floor, which are different. For the surgical treatment of intractable constipation, accurate preoperative classification diagnosis is very important, and it is necessary to formulate an exact and effective surgical plan to avoid untargeted empirical treatment.
View Article and Find Full Text PDFInvestigating medical students' perceptions of point-of-care ultrasound integration into preclinical education.
BMC Med Educ
December 2024
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Introduction: Recent international consensus statements advocate for the integration of Point-of-Care Ultrasound (PoCUS) into the global undergraduate medical curriculum. Some medical schools outside Saudi Arabia have already incorporated PoCUS into their undergraduate curricula to enhance anatomy, physiology and pathology instruction. However, there are no data on the potential role of PoCUS in the preclinical training of medical students in Saudi Arabia.
View Article and Find Full Text PDFComputational study of the impact of nasal vestibule anatomy on nasal drug administration with nasal spray.
Int J Pharm
December 2024
School of Engineering, Faculty of Science and Engineering, Macquarie University, Sydney, NSW 2109, Australia.
The nasal airway comprises a complex network of passages and chambers and plays an important role in regulating the respiratory system's functions. The nasal vestibule is the first chamber of the nasal airway. While variations in nasal vestibule geometries are known to exist between humans, details of their implications on how they may affect the efficacy of nasal drug delivery devices are less clear.
View Article and Find Full Text PDFPrevalence, incidence and trends of keratinocyte carcinoma in Denmark 2007-2021: A population-based register study.
Cancer Epidemiol
December 2024
Institute of Regional Health Research, University of Southern Denmark, Denmark; Department of Surgery, University Hospital of Southern Denmark, Vejle Hospital, Denmark.
Introduction: The incidence of keratinocyte carcinoma (KC), i.e., basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), is increasing worldwide, placing a significant burden on healthcare resources.
View Article and Find Full Text PDFAutomated daily dose accumulation workflow for treatment quality assurance during online adaptive radiotherapy with a 0.35T MR-linac.
J Appl Clin Med Phys
December 2024
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Purpose: This study assesses a novel, automated dose accumulation process during MR-guided online adaptive radiotherapy (MRgART) for prostate cancer, focusing on inter-fractional anatomical changes and discrepancies between delivered and planned doses.
Methods: A retrospective analysis was conducted on seven prostate cancer patients treated with a five-fraction stereotactic body radiation therapy (SBRT), using a 0.35T MRIdian MR-LINAC system.
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