AI Article Synopsis
- Blood plays a vital role in expeditionary casualty care, with low-titer O whole blood being the preferred universal product, though it is often in short supply.
- The study estimates the potential impact of type-specific whole blood (TSWB) on blood supply based on historical demand during U.S. military operations in Afghanistan and production data from a specific blood distribution center.
- Results indicate that adding type A TSWB could boost whole blood production by 11.1% monthly, with TSWB expected to be used in over 20% of transfusion-required military casualties, suggesting that TSWB could significantly enhance blood availability for future needs.
Article Abstract
Introduction: Blood is critical to expeditionary casualty care. Currently, low-titer O whole blood is the preferred product, because it serves as a universal blood product, but demand is higher than supply. Type-specific whole blood (TSWB) has the potential to address this shortfall and provide an identical clinical benefit to specific patient populations. This study estimates the benefit of TSWB to the expeditionary blood supply.
Materials And Methods: Potential TSWB demand was estimated based on the product demand during the US involvement in Afghanistan (2001-2021). Potential production yield increases were based on blood production at the Keesler AFB Blood Distribution Center (FY2016-FY2023).
Results: Including type A TSWB is estimated to increase whole blood production 11.1% monthly. Type-specific whole blood, if available, is expected to be utilized in 20.7% to 35.6% of U.S. Military casualties requiring blood transfusion. Seasonality was found in production (P < .001).
Conclusions: Incorporating TSWB is anticipated to meaningfully expand whole blood availability to meet current shortfalls and future expeditionary casualty needs.
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| http://dx.doi.org/10.1093/milmed/usae534 | DOI Listing |
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