AI Article Synopsis

  • - Vaccination is recognized as the most effective and cost-efficient way to prevent and manage infectious diseases in animals, with ongoing research focusing on innovative veterinary vaccines that encourage long-lasting immunity.
  • - The article highlights advancements in areas such as antigen design, adjuvant formulation, and production processes, ensuring vaccines are effective while minimizing side effects and improving safety in their production.
  • - It also discusses the development of novel biological adjuvants and various production methodologies that enhance vaccine efficacy, emphasizing the importance of interdisciplinary collaboration to increase herd immunity among animal populations.

Article Abstract

Vaccination stands as the paramount and cost-effective strategy for the prevention and management of animal infectious diseases. With the advances in biological technology, materials science and industrial optimization, substantial progress has been made in the development of innovative veterinary vaccines. A majority of the novel vaccines under current investigation tend to stimulate multiple immune pathways and to achieve long-term resistance against infectious diseases, yet it remains imperative to concentrate research efforts on the efficient utilization of vaccines, mitigating toxic side effects, and ensuring safe production processes. This article presents an overview of research progress in veterinary vaccines, encompassing comprehensive antigen design, adjuvant formulation advancements, preparation process optimization, and rigorous immune efficacy evaluation. It summarizes cutting-edge vaccines derived from in vitro synthesis and in vivo application, emphasizing immunogenic components and immune response mechanisms. It also highlights novel biological adjuvants that enhance immune efficacy, diversify raw materials, and possess targeted functions, while comprehensively exploring advancements in production methodologies and compatible vaccine products. By establishing a foundation for the integrated use of these innovative veterinary vaccines, this work facilitates future interdisciplinary cooperation in their advancement, aiming to accelerate the achievement of herd immunity through concerted efforts.

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Source
http://dx.doi.org/10.1016/j.intimp.2024.113784DOI Listing

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