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Filename: controllers/Detail.php
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Filename: models/Detail_model.php
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Filename: controllers/Detail.php
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File: /var/www/html/index.php
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Filename: controllers/Detail.php
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Unlabelled: Early debridement of partial-thickness burns and coverage with skin substitutes is currently the standard of care in children, although there is currently no "gold standard" skin substitute. Our aim is to compare the effectiveness of three different skin substitutes, analyzing the medium- and long-term outcomes.
Methods: A retrospective study was conducted on burn patients under 18 years admitted to our Burn Unit between 2015 and 2021, who were divided into 3 groups according to the type of skin substitute used (EZ-derm®, Biobrane®, and Suprathel®). Demographic and clinical data and short- and long-term outcomes were analyzed. Effectiveness was analyzed by escharectomy and grafting rate during acute management and long-term follow-up reintervention rate. A total of 378 patients were included (179 EZ-derm® group, 107 Biobrane® group, and 92 Suprathel® group). No differences in demographics or burn characteristics were observed between the groups. Patients treated with Suprathel® had a significantly shorter hospital stay (median 4 days (IQR 2-9)), a lower rate of escharectomy and grafting during acute management (21.1%), and a lower long-term follow-up reintervention rate (18.5%) when compared to the EZ-derm® group (median stay 9 days (IQR 6-13); escharectomy and graft 24.6% and reintervention 26.8%) and to the Biobrane® group (median stay 9 days (IQR 7-14); escharectomy and graft 32.1% and reintervention 26.2%).
Conclusion: Treatment of partial-thickness burns with Suprathel® is associated with a shorter hospital stay, lower need for escharectomy and grafting, and lower need for long-term reintervention. Therefore, it should be considered the treatment of choice for pediatric partial-thickness burns.
What Is Known: • Different types of skin substitutes are available for the treatment of skin burns in paediatric patients.
What Is New: • Suprathel® is linked to a reduction in hospital stays, a lower need for escharectomy and grafting, and a lower likelihood of requiring long-term re-interventions.
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http://dx.doi.org/10.1007/s00431-024-05916-6 | DOI Listing |
Adv Healthc Mater
December 2024
Department of Biomedical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, 999077, China.
The advent of bionic skin sensors represents a significant leap forward in the realm of wearable health monitoring technologies. Existing bionic skin technologies face several limitations, including complex and expensive manufacturing processes, low wearing comfort, and challenges in achieving comfortable real-time health monitoring. These shortcomings hinder the widespread adoption and practical utility of bionic skin in various applications.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
December 2024
From Division of Plastic and Reconstructive Surgery, Rutgers New Jersey Medical School, Newark, N.J.
Background: Given the public's tendency to overestimate the capability of artificial intelligence (AI) in surgical outcomes for plastic surgery, this study assesses the accuracy of AI-generated images for breast augmentation and reduction, aiming to determine if AI technology can deliver realistic expectations and can be useful in a surgical context.
Methods: We used AI platforms GetIMG, Leonardo, and Perchance to create pre- and postsurgery images of breast augmentation and reduction. Board-certified plastic surgeons and plastic surgery residents evaluated these images using 11 metrics and divided them into 2 categories: realism and clinical value.
ACS Nano
December 2024
Institute of Functional Nano and Soft Materials (FUNSOM), Joint International Research Laboratory of Carbon-Based Functional Materials and Devices, Soochow University, Suzhou 215123, P. R. China.
Triboelectrification-based artificial mechanoreceptors (TBAMs) is able to convert mechanical stimuli directly into electrical signals, realizing self-adaptive protection and human-machine interactions of robots. However, traditional contact-electrification interfaces are prone to reaching their deformation limits under large pressures, resulting in a relatively narrow linear range. In this work, we fabricated mechano-graded microstructures to modulate the strain behavior of contact-electrification interfaces, simultaneously endowing the TBAMs with a high sensitivity and a wide linear detection range.
View Article and Find Full Text PDFJ Allergy Clin Immunol
December 2024
Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom. Electronic address:
Food allergy is increasing in prevalence, and poses significant challenges for individuals and their families, adversely impacting their quality of life. Misdiagnosis can lead to unnecessary dietary and social limitations, and increased food allergy risk, while failure to diagnose may result in life-threatening anaphylaxis. Therefore, a precise diagnosis is of the utmost importance; however, barriers exist at every stage of the diagnostic process.
View Article and Find Full Text PDFInt J Pharm
December 2024
Heinrich Heine University Duesseldorf, Faculty of Mathematics and Natural Sciences, Institute of Pharmaceutics and Biopharmaceutics, Universitätsstraße 1, Duesseldorf 40225, Germany. Electronic address:
Transdermal drug delivery using microneedle array patches has been investigated using a wide range of drug substances. Inkjet printing and micromolding are established methods for the production of microneedle array patches and both were used to combine lisinopril embedded in povidone and ibuprofen in Eudragit® RS / RL in a single patch. Dissolution studies, visual inspection, mechanical strength and insertion into an artificial skin membrane model were investigated.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!