Introduction: This study aimed to analyse the clinical characteristics of open globe injury (OGI) in children under six.
Methods: A retrospective analysis was conducted on the medical data of children with OGI admitted to the Eye Center of the Second Hospital of Jilin University, China, between 1 January 2012 and 31 December 2020.
Results: The study included 106 children, with 61 males (57.5%) and 45 females (42.5%), and the mean age was 4.14 ± 1.58 years. Injuries predominantly affected the right eye (53.8%). Sharp objects were the leading cause of injuries (56.6%). Most wounds (91.5%) occurred in zone I, and penetrating trauma was the most common injury type (64.2%). The concomitant OGI findings included traumatic cataracts (47.2%), iris prolapse (53.8%), endophthalmitis (22.4%), vitreous prolapse (17.0%), retinal detachment (5.7%), eyelid laceration (7.5%), and orbital fractures (1.9%). Univariate analysis showed that wooden materials ( = 0.045), needles ( = 0.045), postinjury admission time ( < 0.001), injury zone ( = 0.025), and iris prolapse ( = 0.022) were significantly associated with endophthalmitis. Multivariate logistic regression analysis revealed that delayed admission for ≥24 h was an independent risk factor for endophthalmitis ( = 0.007). Preoperative and postoperative visual acuities were significantly correlated ( < 0.001).
Conclusions: OGIs are more common in males under six years old, with sharp objects being the primary cause. Prompt surgical intervention can lower the risk of endophthalmitis. Increased awareness of the severity of OGI and understanding the risk factors for endophthalmitis will aid in developing effective strategies to minimise ocular complications.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634575 | PMC |
http://dx.doi.org/10.3389/fped.2024.1442531 | DOI Listing |
Mol Clin Oncol
February 2025
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China.
The present study aimed to determine the potential of carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), carbohydrate antigen (CA)19-9 and CA242 in predicting recurrence/metastasis of gastric cancer in patients following radical gastrectomy. The clinical data of 368 patients with stage I-III gastric cancer who underwent radical gastrectomy were analyzed, and CEA, AFP, CA19-9 and CA242 levels were detected prior to surgery and 6-12 months following surgery. Univariate and multivariate analyses were used to evaluate the potential risk factors for post-operative recurrence/metastasis of gastric cancer, and the predictive value of CEA, AFP, CA19-9 and CA242 levels was evaluated using receiver operating characteristic (ROC) curve and area under the curve (AUC).
View Article and Find Full Text PDFBackground And Objectives: Generic formulations of glatiramer acetate have been available since 2015 yet remain underprescribed relative to the branded product. We sought to characterize the association between branded glatiramer prescribing in the Medicare program and financial payments from the manufacturer (Teva Pharmaceuticals).
Methods: Using publicly available Medicare Part D and Open Payments data from the Centers for Medicare and Medicaid Services, we evaluated overall utilization from 2012 to 2021 and compared the prevalence, frequency, and magnitude of financial payments made in 2019 to neurologists who prescribed branded and generic versions of glatiramer in 2020.
Objective: Evaluate the feasibility of the midface degloving approach (MDA) in total maxillectomy without orbital exenteration (TMWOE) and reconstruction for sino-nasal neoplasms.
Study Design: Retrospective case series.
Setting: Tertiary referral center.
Objective: To investigate machine learning-based regression models to predict the postoperative apnea-hypopnea index (AHI) for evaluating the outcome of velopharyngeal surgery in adult obstructive sleep apnea (OSA) subjects.
Study Design: A single-center, retrospective, cohort study.
Setting: Sleep medical center.
Objective: To assess if patients with enlarged vestibular aqueduct (EVA) experience symptoms characteristic of other third mobile window disorders such as superior semicircular canal dehiscence syndrome (SCDS).
Study Design: Cross-sectional study.
Setting: Tertiary care center.
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