Background: According to World Health Organization, India is a high tuberculosis (TB) and depression burden state. The risk of depression is higher among TB patients. Therefore, it is vital to focus on the mental well-being of TB patients.
Objective: The present study aimed to determine the prevalence and predictors of depression among drug-sensitive TB patients in Chandigarh city.
Methods: A cross-sectional study was conducted among 305 TB patients. Trained investigators administered Patient Health Questionnaire 9 to screen for depression. Data analysis was done using Epi info software for windows.
Results: The prevalence rate of depression among drug-sensitive TB patients was 7.2%. Current nonworking individuals were more likely to be depressed than their counterparts (OR = 3.7 (1.2-10.9)).
Conclusion: Around one-tenth of the TB patients were suffering from depression. This necessitates physicians to regularly screen TB patients for depression and manage accordingly, which will help improve treatment adherence and outcome.
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http://dx.doi.org/10.4103/ijcm.ijcm_167_23 | DOI Listing |
Indian J Community Med
October 2024
Department of Community Medicine, Government Medical College and Hospital, Chandigarh, India.
Background: According to World Health Organization, India is a high tuberculosis (TB) and depression burden state. The risk of depression is higher among TB patients. Therefore, it is vital to focus on the mental well-being of TB patients.
View Article and Find Full Text PDFIndian J Tuberc
October 2024
Pulmonary Medicine Department, Nootan Medical College and Hospital, Visnagar, India.
Background: India has high prevalence of Tuberculosis (TB). The long duration of treatment and chronic nature of illness predispose a person to anxiety as well as depression. Various addiction habits may affect treatment outcome and impact mental wellbeing in TB patients.
View Article and Find Full Text PDFJ Psychopharmacol
September 2024
Department of Psychology, University of Otago, Dunedin, New Zealand.
Background: Anxiety and depression cause major detriment to the patient, family, and society - particularly in treatment-resistant (TR) cases, which are highly prevalent. TR prevalence may be due to current diagnoses being based not on biological measures but on symptom lists that suffer from clinical subjectivity, variation in symptom presentation, and comorbidity.
Aims: Goal-conflict-specific rhythmicity (GCSR) measured using the Stop-Signal Task (SST) may provide the first neural biomarker for an anxiety process and disorder.
Wellcome Open Res
August 2024
Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Central Region, 256, Uganda.
Background: Globally, more than half of women take medicines whilst breastfeeding. Data concerning the exposure of the breastfed infant to drugs and any related risks are sparce. Lactation studies are only rarely performed close to licensing for medicines anticipated to be widely used in women of childbearing age.
View Article and Find Full Text PDFBr J Clin Pharmacol
January 2024
Centre for Human Drug Research, Leiden, the Netherlands.
Aims: To characterise the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of oxathridine, a first-in-class histamine-3 receptor partialagonist, in healthy male volunteers.
Methods: A randomised, double-blind, placebo-controlled study including the NeuroCart, consisting of a battery of drug sensitive neurophysiological tests, was performed. Oxathridine was administered orally as an aqueous solution.
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