Aim: To assess staff adherence to a 'Preterm Brain Injury Prevention Bundle', and its effectiveness in reducing severe intraventricular haemorrhage (IVH) rates and risk factors in extremely preterm infants born at <26 weeks' gestation.
Methods: Adherence to the bundle was assessed using a novel bedside assessment tool, with immediate feedback to bedside staff post-assessment. Data on IVH rates and associated risk factors were stratified by IVH severity, and compared between pre- and post-bundle implementation.
Results: Of 203 bedside assessments, good adherence was observed in 12/28 items (43%), while the remaining items required improvement. Rates of grade 3/4 IVH reduced (39.2% pre-bundle vs. 19.0% post-bundle, p = 0.13). Thermoregulation and base excess improved (p = 0.02 and p = 0.04 respectively) after bundle implementation.
Conclusion: Reduced severe IVH rates post-bundle implementation may be attributed to staff education and improved clinical parameters. Adherence to the bundle interventions varied which highlighted target areas for future education.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/apa.17542 | DOI Listing |
J Neural Transm (Vienna)
January 2025
Laboratory of Biological Psychiatry, Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, 13 Liulin Road, Tianjin, 300222, China.
Bipolar disorder (BD) frequently coexists with anxiety disorders, creating complex challenges in clinical therapy and management. This study investigates the prevalence, prognostic implications, and treatment strategies for comorbid BD and anxiety disorders. High comorbidity rates, particularly with generalized anxiety disorder, underscore the necessity of thorough clinical assessments to guide effective management.
View Article and Find Full Text PDFJ Cancer Res Clin Oncol
January 2025
Sarcoma Unit, Department of Surgery, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Purpose: The management of soft tissue sarcoma (STS) at reference centers with specialized multidisciplinary tumor boards (MTB) improves patient survival. The German Cancer Society (DKG) certifies sarcoma centers in German-speaking countries, promoting high standards of care. This study investigated the variability in treatment recommendations for localized STS across different German-speaking tertiary sarcoma centers.
View Article and Find Full Text PDFSci Rep
January 2025
The Queen's Medical Center, 1301 Punchbowl Street, QET 4M, Honolulu, Hawai'i, 96813, USA.
High flow nasal cannula (HFNC) can reduce the need for intubation in patients with coronavirus disease-19 (COVID-19) pneumonia induced acute hypoxemic respiratory failure (AHRF), but predictors of HFNC success could be characterized better. C-reactive protein (CRP) and D-dimer are associated with COVID-19 severity and progression. However, no one has evaluated the use of serial CRP and D-dimer ratios to predict HFNC success.
View Article and Find Full Text PDFSci Rep
January 2025
State Key Laboratory of Geohazard Prevention and GeoEnvironment Protection, Chengdu University of Technology, Chengdu, 610059, Sichuan, China.
Pakistan's geographic location makes it an important land hub between Central Asia, Middle East-North Africa, and China. However, the railways, roads, farmland, riverways, and residential quarters in the Piedmont plains of Baluchistan province in northwestern Pakistan are under serious threat of flooding in the summer of 2022. The urgency and severity of climate change's impact on humanity are underscored by the significant threats posed to human life and property in Piedmont Plains environments through extreme flood events, which has garnered widespread concerns.
View Article and Find Full Text PDFClin J Gastroenterol
January 2025
University of Connecticut, Connecticut, USA.
Marginal ulcers are a common complication following Roux-en-Y bypass surgeries with an approximate incidence of 4.6%. The pathophysiology is complex and risk factors include smoking, nonsteroidal anti-inflammatory drugs (NSAIDs) use, Helicobacter pylori infection, and a larger pouch size.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!