Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.asjsur.2024.12.006 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mineral Profile, Antioxidant, Anti-Inflammatory, Antibacterial, Anti-Urease and Anti-α-Amylase Activities of the Unripe Fruit Extracts of .
Molecules
January 2023
Laboratory of Fundamental Sciences, University Amar Télidji of Laghouat, Road of Ghardaïa, Laghouat 03000, Algeria.
in folk medicine is used by Algerian traditional healers for treating a wide variety of diseases and conditions including dyspepsia, digestive problems, peptic ulcers, and, in particular, inflammatory diseases. The present study aimed to assess the phytochemical composition, in vitro antioxidant activity (using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ABTS+, and reducing power methods), enzyme inhibitory activity (towards α-amylase and urease), antibacterial activity, and in vivo anti-inflammatory activity of the unripe fruit extracts of collected from different parts of the Djelfa region of Algeria. According to the findings, various aqueous extracts exhibited significant antioxidant and enzymatic activities in all tests, but showed that they have a weak inhibitory effect against all tested bacterial strains.
View Article and Find Full Text PDFEffect of Extraction Methods on Polyphenols, Flavonoids, Mineral Elements, and Biological Activities of Essential Oil and Extracts of L.
Molecules
December 2021
Chemistry Department, University of Hamma Lakhdar El-Oued, B.P.789, El-Oued 39000, Algeria.
Our study evaluated the in vitro antioxidant properties, antibacterial and antifungal activities, anti-inflammatory properties, and chemical composition of the essential oils (EOs), total phenol, and total flavonoid of wild L. This study also determined the mineral (nutritional and toxic) elements in the plant. The EOs were extracted using three techniques-hydro distillation (HD), steam distillation (SD), and microwave-assisted distillation (MAD)-and were analyzed using chromatography coupled with flame ionization (GC-FID) and gas chromatography attached with mass spectrometry detector (GC-MS).
View Article and Find Full Text PDFTargeting Pancreatic Cancer Cells and Stellate Cells Using Designer Nanotherapeutics in vitro.
Int J Nanomedicine
June 2020
Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.
Article Synopsis
- Pancreatic cancer features a dense tissue environment that hinders effective delivery of the chemotherapy drug gemcitabine, making treatment challenging.
- A targeted drug delivery system was developed using gold nanoparticles and the anti-EGFR antibody cetuximab, combined with gemcitabine and polyethylene glycol to enhance drug delivery to pancreatic cancer and associated cells.
- The new drug delivery system, particularly the PEGylated nanoconjugate ACG44P1000, showed improved effectiveness in reducing the viability of pancreatic cancer cells in lab tests, setting the stage for future studies on its potential to combat tumor growth and desmoplasia in living organisms.*
Developmental pattern of the neuronal intermediate filament inaa in the zebrafish retina.
J Comp Neurol
December 2016
Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
α-Internexin is a member of the neuronal intermediate filament (nIF) protein family, which also includes peripherin and neurofilament (NF) triplet proteins. Previous studies found that expression of α-internexin precedes that of the NF triplet proteins in mammals and suggested that α-internexin plays a key role in the neuronal cytoskeleton network during development. In this study, we aimed to analyze the expression patterns and function of internexin neuronal intermediate filament protein-alpha a (inaa), the encoding gene of which is a homolog of the mammalian α-internexin, during retinal development in zebrafish.
View Article and Find Full Text PDFPosttranscriptional activation of the transcriptional activator Rob by dipyridyl in Escherichia coli.
J Bacteriol
March 2002
Laboratory of Molecular Biology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bldg 5. Rm. 333, Bethesda, MD 20892-0560, USA.
The transcriptional activator Rob consists of an N-terminal domain (NTD) of 120 amino acids responsible for DNA binding and promoter activation and a C-terminal domain (CTD) of 169 amino acids of unknown function. Although several thousand molecules of Rob are normally present per Escherichia coli cell, they activate promoters of the rob regulon poorly. We report here that in cells treated with either 2,2"- or 4,4"-dipyridyl (the latter is not a metal chelator), Rob-mediated transcription of various rob regulon promoters was increased substantially.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!