Of 834 children who had appendicectomy for appendicitis 77 (9.2%) had developed an appendix mass when first seen. Under 6 years of age 25% of appendicitis patients had an appendix mass at presentation and almost 60% of the masses seen were in patients under six years of age. Forty three of the 77 masses (55%) were palpable only under anaesthesia. The masses were all initially managed conservatively by bed rest, intravenous fluids and intravenous antibiotics. All but eight (10%) of the 77 patients responded to this form of treatment. Interval appendicectomy was planned for a date 4 weeks following discharge. The overall total average bed stay including interval appendicectomy was 16 days. There were no late complications or relaparotomies.
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Int J Surg Case Rep
January 2025
Department of Obstetrics and Gynecology, Tahar Sfar University Hospital, 5111 Mahdia, Tunisia.
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View Article and Find Full Text PDFWorld J Surg Oncol
January 2025
Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, 158 Shangtang Road, Hangzhou, Zhejiang, 310014, China.
Background: Low-grade mucinous neoplasms typically originate from the appendix and are characterized by a lining of low-grade mucus-secreting columnar epithelial cells and smooth muscle. However, atypical origins can occur, as demonstrated in this case report.
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Cell Death Dis
January 2025
Center for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield Clinic Health System, Marshfield, WI, USA.
The orphan nuclear receptor NR2E3 has emerged as a potential tumor suppressor, yet its precise mechanisms in tumorigenesis require further investigation. Here, we demonstrate that the full-length protein isoform of NR2E3 instead of its short isoform activates wild-type p53 and is capable of rescuing certain p53 mutations in various cancer cell lines. Importantly, we observe a higher frequency of NR2E3 mutations in three solid tumors compared to the reference population, highlighting its potential significance in tumorigenesis.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Department of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Introduction: Amyand's hernia is a rare condition defined by the presence of the vermiform appendix within an inguinal hernia sac. The occurrence of Amyand's hernia with testicular necrosis is particularly uncommon, further complicating its clinical presentation and management.
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Int J Womens Health
December 2024
Sydney Women's Endosurgery Centre (SWEC), St George Hospital, Sydney, NSW, Australia.
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