Investigating the impact of the effective point of measurement for plane-parallel ionization chambers in clinical proton beams.

To investigate the impact of the positioning of plane-parallel ionization chambers in proton beams on the calculation of the chamber-specific factorand, hence, the beam quality correction factorkQ,Q0.Monte Carlo simulations were performed to calculate the chamber-specific factorin monoenergetic proton beams for six different plane-parallel ionization chambers while positioning the chambers with a) their reference point and b) their effective point of measurement accounting for the water equivalent thickness of the entrance window.For all ionization chamber models investigated in this study, the difference inbetween both positioning approaches was larger for steeper dose gradients and bigger differences between the geometrical thickness and water-equivalent thickness of the entrance window. The largest effect was 1.2% for the IBA PPC-05 ionization chamber at an energy of 60 MeV.The positioning of plane-parallel ionization chambers in proton beams has a systematic impact on thefactor. This is especially of relevance for thekQ,Q0factors presented in the recently updated TRS-398 code of practice (CoP) from IAEA. The background is that a positioning with the effective point of measurement is prescribed in TRS-398 CoP, however, all Monte Carlo derived data that have been employed for the update are based on a positioning of the ionization chambers with their reference point. Hence, the updatedkQ,Q0factors for plane-parallel ionization chambers in proton beams are subject to systematic errors that can be as large as 0.5%.