[This corrects the article DOI: 10.1371/journal.pone.0252786.].
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11637390 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0315965 | PLOS |
Lung
June 2024
Department of Pediatrics, Pediatric Pulmonology, University Hospital of Leuven, Herestraat 49, 3000, Leuven, Belgium.
Auris Nasus Larynx
June 2024
Department of Otorhinolaryngology Head and Neck Surgery, University of Fukui, Japan.
Objective: Primary ciliary dyskinesia (PCD) is a relatively rare genetic disorder that affects approximately 1 in 20,000 people. Approximately 50 genes are currently known to cause PCD. In light of differences in causative genes and the medical system in Japan compared with other countries, a practical guide was needed for the diagnosis and management of Japanese PCD patients.
View Article and Find Full Text PDFSci Rep
September 2023
Center for Excellence in Pulmonary Biology, Stanford University, Palo Alto, CA, USA.
Primary ciliary dyskinesia (PCD) is a genetic disorder associated with recurrent and chronic respiratory infections due to functional defects of motile cilia. In this study, we aimed to elucidate inflammatory and proliferative responses in PCD respiratory epithelium and evaluate the effect of Azithromycin (AZT) on these responses. Airway basal cells (BCs) were isolated from nasal samples of Wild-type (WT) epitope of healthy donors and PCD donors with bi-allelic mutations in DNAH5, DNAH11 and CCDC39.
View Article and Find Full Text PDFInt J Gynaecol Obstet
January 2020
School of Biotechnology, Shri Mata Vaishno Devi University, Katra, Jammu and Kashmir, India.
Objective: To investigate the association of newly identified genetic variants G>A (rs2285947) of the DNAH11 gene and G>A (rs2494938) of the LRFN2 gene with ovarian and breast cancers in women belonging to Jammu and Kashmir state, where the prevalence of ovarian and breast cancers is remarkably high in the population.
Methods: A candidate gene prospective case-control association study design was adopted, in which 354 cases (219 cases of ovarian cancer and 135 cases of breast cancer) were histopathologically confirmed and 330 healthy controls matched for age and ethnicity were recruited. The details of cases and controls were also recorded in a predesigned pro forma after their written informed consent.
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