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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11707612 | PMC |
| http://dx.doi.org/10.1182/bloodadvances.2024014741 | DOI Listing |
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Treatment of pain in fibromyalgia patients with testosterone gel: Pharmacokinetics and clinical response.
Int Immunopharmacol
August 2015
Department of Pathology, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA. Electronic address:
To test our hypothesis that testosterone deficiency plays an important role in chronic pain, a Phase I/II pilot study was initiated with 12 fibromyalgia patients to verify that a daily dose for 28days with transdermal testosterone gel would 1) significantly and safely increase mean serum testosterone concentrations from low baseline levels to mid/high-normal levels, and 2) effectively treat the pain and fatigue symptoms of fibromyalgia. Pharmacokinetic data confirmed that serum free testosterone concentrations were raised significantly above baseline levels, by assessment of maximum hormone concentration (Cmax) and area under the curve (AUC) parameters: free testosterone Cmax was significantly raised from a mean of 2.64pg/mL to 3.
View Article and Find Full Text PDFPrevention of glucocorticoid-induced fractures: which patients should we treat? Comment on the article by Grossman et al.
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A learning and teaching resource on patient self-management of chronic pain.
Am J Pharm Educ
March 2013
Faculty of Pharmacy, The University of Sydney, Camperdown, NSW, Australia.
Objective: To develop, pilot test, and evaluate an instructional module on patient self-management for undergraduate pharmacy students in an Australian university.
Design: Learning outcomes and associated content and assessment tasks were developed, featuring lecture and readings, in-class discussions, and online delivery of in-depth interviews with patients who were living with chronic pain.
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Strategies for the management of intermittent allergic rhinitis: an Australian study.
Health Expect
April 2014
Senior Lecturer, Faculty of Pharmacy, The University of Sydney, Sydney, NSW, AustraliaProject Manager, Faculty of Pharmacy, The University of Sydney, Sydney, NSW, AustraliaSenior Lecturer, Faculty of Pharmacy, The University of Sydney, Sydney, NSW, AustraliaRegulatory Affairs Associate (Primary Care), Merck, Sharp and Dohme Pty Ltd, Sydney, NSW, Australia.
Objective: Allergic rhinitis is increasing globally despite treatment focussed on pharmacotherapy. This study aimed to (i) examine the range and proportion of symptoms and triggers experienced by patients with intermittent allergic rhinitis (IAR); (ii) conduct a qualitative analysis of strategies devised to control symptoms and triggers; and (iii) measure medication adherence.
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Patient Educ Couns
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Faculty of Pharmacy, The University of Sydney, Sydney, NSW 2006 Australia.
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