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http://dx.doi.org/10.1186/s12885-024-13306-2 | DOI Listing |
J Neurol
January 2025
Neurology, Cantonal Hospital of Baden, Baden, Switzerland.
Background: Correct identification of those patients presenting with an acute vestibular syndrome (AVS) or an acute imbalance syndrome (AIS) that have underlying posterior-circulation stroke (PCS) and thus may benefit from revascularization (intravenous thrombolysis (IVT), endovascular therapy (EVT)) is important. Treatment guidelines for AVS/AIS patients are lacking. We reviewed the evidence on acute treatment strategies in AVS/AIS focusing on predictors for IVT/EVT and outcome.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Southern California, Los Angeles, CA, USA.
Background: Cerebrovascular reactivity (CVR) is a marker of cerebrovascular function defined by blood flow changes in response to vasoactive stimuli, which may represent a valuable indicator of risk for vascular brain injury and cognitive decline. Understanding of sex specific CVR patterns is limited, yet likely important for understanding vascular risk. Previous research on sex differences in CVR is mixed, and has predominantly focused on younger adults and utilized Transcranial Doppler ultrasound approaches that focus on large intracranial artery flow.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Radiology, Northwestern University, Chicago, IL, USA.
Background: Amyloid accumulation is one of the main pathophysiological hallmarks of Alzheimer's disease (AD) and is closely associated with neuronal dysfunction and cognitive decline. Except for amyloid pathology, accumulating evidence has shown vascular dysfunctions, such as reduced cerebral blood flow (CBF), also contribute to AD pathophysiology. However, there remains limited research about the longitudinal changes between amyloid accumulation and CBF.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Civil Engineering, Isfahan University of Technology, Isfahan, Iran.
Floods are among the most severe natural hazards, causing substantial damage and affecting millions of lives. These events are inherently multi-dimensional, requiring analysis across multiple factors. Traditional research often uses a bivariate framework relying on historical data, but climate change is expected to influence flood frequency analysis and flood system design in the future.
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