Getting RAMPed up: Neuropeptides boost T helper 1 cell fate.

Immunity

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address:

Published: December 2024

CD4 T helper (Th) cell differentiation depends on regulatory networks that enforce lineage commitment while suppressing alternative fates. In a recent issue of Nature, Hou et al. reveal that calcitonin gene-related peptide (CGRP) directs Th1 commitment, highlighting neuro-immune crosstalk in T cell fate decisions.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2024.11.013DOI Listing

Publication Analysis

Top Keywords

helper cell
8
ramped neuropeptides
4
neuropeptides boost
4
boost helper
4
cell fate
4
fate cd4
4
cd4 helper
4
cell differentiation
4
differentiation depends
4
depends regulatory
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!