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Nociplastic pain: controversy of the concept.
Korean J Pain
January 2025
Independent Researcher, Vilnius, Lithuania.
Classically, pain can be of a nociceptive or neuropathic nature, which refers to non-neural or neural tissue lesions, respectively. Chronic pain in conditions such as migraine, fibromyalgia, and complex regional pain syndrome (CRPS), is thought to perpetuate without a noxious input. Pain in such patients can be assigned neither to the nociceptive nor neuropathic category.
View Article and Find Full Text PDFMisapplication of Biologic Mesh in Clean-Site Elective Ventral Hernia Repair.
JAMA Surg
December 2024
Department of Surgery, University of Chicago, Chicago, Illinois.
Diagnostic performance of Typhidot RDT in diagnosis of typhoid fever and antibiotic resistance characterisation in a cross-sectional study in Southern Ghana.
BMC Infect Dis
November 2024
West African Centre for Cell Biology of Infectious Pathogens, College of Basic and Applied Sciences, University of Ghana, Legon-Accra, Ghana.
Article Synopsis
- Typhoid fever is a major public health issue in Ghana, leading to improper antibiotic use, yet there's limited data on the reliability of the Typhidot rapid diagnostic test for confirming the disease.
- A study conducted in Southern Ghana with 258 participants evaluated the Typhidot test against blood and stool cultures, finding it had low sensitivity (35% for blood) and specificity (45% for stool), indicating it may not accurately diagnose typhoid fever.
- The research also revealed that most Salmonella enterica isolates came from stool samples, highlighting a chance to address typhoid transmission during acute infections, but emphasizes the need for better diagnostic methods to prevent antibiotic misuse.
Misdiagnosis of Multiple Sclerosis: Past, Present, and Future.
Curr Neurol Neurosci Rep
November 2024
Department of Neurological Sciences, Larner College of Medicine, The University of Vermont, 1 South Prospect St., Burlington, VT, 05477, USA.
Purpose Of Review: Misdiagnosis of multiple sclerosis (MS) is a prevalent worldwide problem. This review discusses how MS misdiagnosis has evolved over time and focuses on contemporary challenges and potential strategies for its prevention.
Recent Findings: Recent studies report cohorts with a range of misdiagnosis between 5 and 18%.
Reply: Potential for Misapplication of a Uniform vs Sex-Specific High-Sensitivity Cardiac Troponin Threshold.
J Am Coll Cardiol
September 2024
University of Edinburgh, Edinburgh, United Kingdom. Electronic address:
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