AI Article Synopsis

  • Seasonal influenza is a global health issue, particularly dangerous for hemodialysis patients, and this case illustrates the severity it can cause despite vaccination and antiviral treatment.
  • A 71-year-old male on hemodialysis developed severe pneumonia from influenza A, leading to hospitalization due to his high-risk status.
  • The case highlights the importance of early steroid therapy in improving outcomes for dialysis patients severely affected by influenza, even when they receive vaccines and antivirals.

Article Abstract

Seasonal influenza is prevalent globally, particularly during winter months. It is well documented that this disease causes severe, often fatal complications in hemodialysis patients. While numerous reports have focused on novel influenza viruses, there is a paucity of case reports detailing seasonal influenza viral infections in this patient population. This case presents a 71-year-old male undergoing hemodialysis who developed severe seasonal influenza A pneumonia despite receiving the influenza vaccine and early antiviral treatment. Initially presenting with fever, cough, and myalgia, the patient was diagnosed with influenza A virus infection and hospitalized due to heightened risk associated with dialysis and an elevated inflammatory response. Despite treatment with two different antiviral medications, his condition deteriorated, leading to ARDS (acute respiratory distress syndrome). The administration of steroid pulse therapy resulted in significant clinical improvement. This case underscores the severe nature of influenza virus-related illnesses in dialysis patients, even with vaccination and early antiviral intervention. It also suggests the potential benefit of early steroid pulse therapy in managing severe influenza pneumonia in high-risk individuals.

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Source
http://dx.doi.org/10.1007/s13730-024-00951-6DOI Listing

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