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Clinical Perspectives on the Pathophysiology of Facial Synkinesis: A Narrative Review.
JAMA Otolaryngol Head Neck Surg
January 2025
Department of Plastic Surgery, The University of Texas Southwestern Medical Center, Dallas.
Importance: Facial synkinesis refers to pathologic cocontraction and baseline hypertonicity of muscles innervated by the facial nerve, commonly attributed to the aberrant regeneration of nerve fibers following injury. The pathomechanism and optimal treatment of facial synkinesis remain unclear. The goal of this review is to highlight current understanding of the epidemiology, pathophysiology, clinical presentation, assessment, and treatment of facial synkinesis.
View Article and Find Full Text PDFDouble CHEK2 Pathogenic and Low-Risk Variants and Associated Cancer Phenotypes.
JAMA Netw Open
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Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Boston, Massachusetts.
Importance: CHEK2 pathogenic and likely pathogenic variants (PVs) are common, and low-risk (LR) variants, p.I157T, p.S428F, and p.
View Article and Find Full Text PDFDecreased incubation of fentanyl seeking in the absence of proximal drug-paired stimuli.
Exp Clin Psychopharmacol
January 2025
Department of Biological Sciences, Northern Kentucky University.
Treating substance use disorders is difficult as individuals often resume substance use during abstinence. One potential factor contributing to the recurrence of substance use is incubation of drug craving. Specifically, individuals report higher levels of craving when presented with drug-paired stimuli across abstinence, although this effect is largely absent in opioid-dependent individuals.
View Article and Find Full Text PDFAssessment of Bacteriological Quality and Antibiotic Resistance in Locally and Industrially Produced Ice Creams: A Study on Probiotic Incorporation for Enhanced Safety and Health Benefits in Kushtia City, Bangladesh.
Probiotics Antimicrob Proteins
January 2025
Department of Biotechnology and Genetic Engineering, Faculty of Biological Science, Islamic University, Kushtia, 7003, Bangladesh.
Ice creams are consumable foods that have the potential to be used as probiotic carriers. The purpose of this study was to evaluate the bacteriological quality (i.e.
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