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| http://dx.doi.org/10.1021/acsabm.4c01791 | DOI Listing |
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Development of a novel molecular probe for visualizing mesothelin on the tumor via positron emission tomography.
Eur J Nucl Med Mol Imaging
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Institute of Radiation Medicine, Fudan University, Xietu Road 2094, Shanghai, 200032, China.
Objectives: Mesothelin (MSLN) is an antigen that is overexpressed in various cancers, and its interaction with tumor-associated cancer antigen 125 plays a multifaceted role in tumor metastasis. The serum MSLN expression level can be detected using enzyme-linked immunosorbent assay; however, non-invasive visualization of its expression at the tumor site is currently lacking. Therefore, the aim of this study was to develop a molecular probe for imaging MSLN expression through positron emission tomography (PET).
View Article and Find Full Text PDFGraded Anterior Partial-thickness Blepharotomy for the Correction of Idiopathic Unilateral Upper Eyelid Retraction: A Case Report and Literature Review.
Plast Reconstr Surg Glob Open
January 2025
From the Department of Plastic and Burn Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Idiopathic upper eyelid retraction is a rare ocular symptom characterized by abnormal upward displacement of the upper eyelid, often without any identifiable systemic disease. This condition not only affects the patient's appearance but may also have a certain impact on their daily life and mental health. We report a case of adult idiopathic unilateral upper eyelid retraction, and based on the patient's specific condition, we used graded anterior plate blepharoplasty for treatment.
View Article and Find Full Text PDFOptical glass selection is an important research object in optical design, which is an important way to aberration correction. However, these methods to our knowledge either do not correct aberration well or consume too much time. To efficiently solve the apochromatic problems in optical design, this paper presents what we believe to be a novel automatic optimization method for discontinuous optical glass based on auto glass selection (AGS).
View Article and Find Full Text PDFSubcutaneous Lower Pole Release as Double Bubble Prevention in Constricted Base Breasts: The "Plus One" Augmentation Technique.
Aesthet Surg J
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Department of Plastic and Aesthetic Surgery, Sana Kliniken Duesseldorf GmBH, Graeulinger Strasse, Duesseldorf, Germany.
Background: Breasts with a broad base, constricted inframammary fold (IMF) and a short distance between the nipple and the IMF are predisposed to form a double bubble (DB) deformity. Most publications have focused on the correction of a DB rather than on its prevention and thorough analysis of the IMF.
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Using DIMet for Differential Analysis of Labeled Metabolomics Data: A Step-by-step Guide Showcasing the Glioblastoma Metabolism.
Bio Protoc
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University of Bordeaux, CNRS, IBGC UMR 5095, Bordeaux, France.
Stable-isotope resolved metabolomics (SIRM) is a powerful approach for characterizing metabolic states in cells and organisms. By incorporating isotopes, such as C, into substrates, researchers can trace reaction rates across specific metabolic pathways. Integrating metabolomics data with gene expression profiles further enriches the analysis, as we demonstrated in our prior study on glioblastoma metabolic symbiosis.
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