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Multiscale feature enhanced gating network for atrial fibrillation detection.
Comput Methods Programs Biomed
January 2025
College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, 110169, PR China. Electronic address:
Background And Objective: Atrial fibrillation (AF) is a significant cause of life-threatening heart disease due to its potential to lead to stroke and heart failure. Although deep learning-assisted diagnosis of AF based on ECG holds significance in clinical settings, it remains unsatisfactory due to insufficient consideration of noise and redundant features. In this work, we propose a novel multiscale feature-enhanced gating network (MFEG Net) for AF diagnosis.
View Article and Find Full Text PDFNew Insights into the Role of Inflammatory Pathways and Immune Cell Infiltration in Sleep Deprivation-Induced Atrial Fibrillation: An Integrated Bioinformatics and Experimental Study.
J Inflamm Res
January 2025
Xinjiang Key Laboratory of Cardiac Electrophysiology and Cardiac Remodeling, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China.
Background: The common occurrence of atrial fibrillation (AF) as a cardiac arrhythmia, along with its link to sleep deprivation (SD), is gaining more acknowledgment. Even with progress in comprehending the development of AF, the molecular connections between SD and AF are still not well-defined. The objective of this research was to pinpoint the shared molecular routes responsible for SD-induced AF and investigate possible treatment targets.
View Article and Find Full Text PDFFactors Associated With the Development of Heart Failure Following Acute Coronary Syndrome: A Systematic Review and Meta-Analysis.
Cureus
December 2024
Internal Medicine, University of Health Sciences, Lahore, PAK.
Acute coronary syndrome (ACS) remains a major global health burden, encompassing a spectrum of conditions from unstable angina to acute myocardial infarction. Despite advancements in early detection and management, ACS is often complicated by the development of heart failure. This systematic review and meta-analysis aimed to identify factors associated with the development of heart failure following acute coronary syndrome.
View Article and Find Full Text PDFRole of HbA1c in Mortality Among Patients With a Medical History of Ischemic Stroke and Paroxysmal Atrial Fibrillation: A Systematic Review.
Cureus
December 2024
Medicine, Jinnah Hospital, Lahore, Lahore, PAK.
Elevated HbA1c, a marker of poor glycemic control, is associated with adverse cardiovascular outcomes and mortality. HbA1c influences outcomes through distinct mechanisms of vascular dysfunction and atherosclerosis in ischemic stroke, during atrial remodeling and thrombus formation in paroxysmal atrial fibrillation (PAF). Optimal HbA1c thresholds are generally below optimal levels, with levels above this being linked to higher mortality in both populations.
View Article and Find Full Text PDFThe role of SGLT1 in atrial fibrillation and its relationship with endothelial-mesenchymal transition.
Biochem Biophys Res Commun
January 2025
The First Affiliated Hospital, Department of Cardiovascular Medicine, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, PR China; Department of Cardiovascular Disease and Key Lab for Atherosclerosis of Hunan Province, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, PR China. Electronic address:
Atrial fibrillation (AF) is a prevalent arrhythmia closely associated with atrial fibrosis, posing significant challenges to cardiovascular health. Recent studies have identified the sodium-glucose co-transporter 1 (SGLT1) as a potential key player in the pathophysiology of heart diseases, particularly in the context of AF and atrial fibrosis. This review aims to synthesize current knowledge regarding the mechanisms by which SGLT1 influences the development of AF and atrial fibrosis, with a specific focus on its relationship with endothelial-mesenchymal transition (EMT).
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