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Novel photopeak-independent correction method for internal activity calculation of 99mTc: a simulation study. | LitMetric

Novel photopeak-independent correction method for internal activity calculation of 99mTc: a simulation study.

Radiat Prot Dosimetry

Facultad de Medicina, Universidad Autónoma del Estado de México, Paseo Tollocan s/n esquina Jesús Carranza, Col. Moderna de la Cruz, Toluca 50180, Estado de México, Mexico.

Published: December 2024

AI Article Synopsis

  • This paper introduces a new technique to improve the accuracy of measuring 99mTc internal activity in nuclear medicine by correcting for scattered radiation using gamma cameras.
  • The study uses Monte Carlo simulations to calculate scattering correction factors for anterior and posterior count rates, allowing for a more accurate estimation of activity compared to older methods.
  • Results indicate that the new method reduces error to less than 3% in determining real activity, while traditional methods showed up to 11% error.

Article Abstract

This paper presents a new method for correcting the contribution of scattered radiation to the measurement of 99mTc internal activity in nuclear medicine patients using gamma cameras. So, this study aims to derive scattering correction factors by Monte Carlo simulation for anterior and posterior count rates (${I}_{\mathrm{A}}$ and ${I}_{\mathrm{P}}$) in the conjugate view method, enabling more precise estimation of activity A(t) compared to traditional trapezoidal and triangular approximations. The new approach eliminates the need to use photopeak for determining the fraction of scattered photons. Our results showed differences of <3% with respect to the real activity and 11% for the trapezoidal and triangular approaches.

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Source
http://dx.doi.org/10.1093/rpd/ncae224DOI Listing

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