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http://dx.doi.org/10.3238/arztebl.m2023.0272DOI Listing

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Colitis cystica profunda: A rare mimicker of submucosal tumour.

Dig Liver Dis

January 2025

Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Nanchong Central Hospital, Sichuan, China. Electronic address:

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Colitis cystica profunda (CCP) is a rare, uncommon and nonneoplastic condition that can occur anywhere in gastrointestinal tract, but its main occurrence is in the rectum and sigmoid colon. It is characterized by the presence of mucin filled cysts, lined by benign epithelium, beneath the muscularis mucosae, usually confined to the submucosa, and it can clinically and radiologically mimic a neoplasm. Here we report a rare case of CCP in a patient with a 2-months history of abdominal pain and severe anemia, associated with diverticulosis.

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Unlabelled: Cystica profunda is a rare benign finding of mucous-filled cysts in the submucosa of the gastrointestinal tract, more commonly found in the rectum and colon. Risk factors include rectal prolapse, inflammatory bowel diseases, pelvic radiation and being post-appendectomy. We present a case of a female patient presenting with rectorrhagia, found to have sigmoidal colitis cystica profunda (CCP) six months post-appendectomy.

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