The inconclusive category in forensics reporting is the appropriate response in many cases, but it poses challenges in estimating an "error rate". We discuss the use of a class of information-theoretic measures related to cross entropy as an alternative set of metrics that allows for performance evaluation of results presented using multi-category reporting scales. This paper shows how this class of performance metrics, and in particular the log likelihood ratio cost, which is already in use with likelihood ratio forensic reporting methods and in machine learning communities, can be readily adapted for use with the widely used multiple category conclusions scales. Bayesian credible intervals on these metrics can be estimated using numerical methods. The application of these metrics to published test results is shown. It is demonstrated, using these test results, that reducing the number of categories used in a proficiency test from five or six to three increases the cross entropy, indicating that the higher number of categories was justified, as it they increased the level of agreement with ground truth.
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http://dx.doi.org/10.1111/1556-4029.15686 | DOI Listing |
Sci Rep
January 2025
Department of Mathematical Sciences, Faculty of Science, Somali National University, Mogadishu Campus, Mogadishu, Somalia.
In recent years, machine learning has gained substantial attention for its ability to predict complex chemical and biological properties, including those of pharmaceutical compounds. This study proposes a machine learning-based quantitative structure-property relationship (QSPR) model for predicting the physicochemical properties of anti-arrhythmia drugs using topological descriptors. Anti-arrhythmic drug development is challenging due to the complex relationship between chemical structure and drug efficacy.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Chemistry Department, Faculty of Science, Damietta University, Damietta 34517, Egypt. Electronic address:
The VCo-LDH/CS hydrogel beads were created by combining VCo-layered double hydroxide (VCo-LDH) and chitosan (CS) using a cross-linking process with epichlorohydrin. These beads were specifically designed to remove tetracycline (TTC). To characterize the VCo-LDH/CS hydrogel beads, several analytical techniques were used, with PXRD, XPS, FESEM, EDX, and FT-IR.
View Article and Find Full Text PDFPsychiatry Clin Neurosci
January 2025
Institute of Brain Science, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Aim: Autistic traits exhibit neurodiversity with varying behaviors across developmental stages. Brain complexity theory, illustrating the dynamics of neural activity, may elucidate the evolution of autistic traits over time. Our study explored the patterns of brain complexity in autistic individuals from childhood to adulthood.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Department of Urology, Korea University Guro Hospital, Korea University College of Medicine, Seoul 08308, Republic of Korea.
Background/objectives: Cystoscopy is necessary for diagnosing bladder cancer, but it has limitations in identifying ambiguous lesions, such as carcinoma in situ (CIS), which leads to a high recurrence rate of bladder cancer. With the significant advancements in deep learning in the medical field, several studies have explored its application in cystoscopy. This study aimed to utilize the VGG19 and Deeplab v3+ deep learning models to classify and segment cystoscope images, respectively.
View Article and Find Full Text PDFCogn Neurodyn
December 2025
Department of Nuclear Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, 730030 China.
Unlabelled: Juvenile myoclonic epilepsy (JME) exhibits abnormal functional connectivity of brain networks at multiple frequencies. We used the multilayer network model to address the heterogeneous features at different frequencies and assess the mechanisms of functional integration and segregation of brain networks in JME patients. To address the possibility of false edges or missing edges during network construction, we combined multilayer networks with link prediction techniques.
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