Anxiety and Depression Among Patients With Irritable Bowel Syndrome in Hail, Saudi Arabia: Towards a Better Understanding of the Psychological Role.

Introduction: Patients with irritable bowel syndrome (IBS) often experience psychiatric disorders such as anxiety and depression. This study examined the association between IBS and anxiety and depression and explored how these variables interact with various IBS indices in the general population of Hail, Saudi Arabia.

Methods: This cross-sectional descriptive study utilized standardized assessments for diagnosing IBS, anxiety, and depression. An online questionnaire was distributed to individuals in the Hail region.

Results: A total of 687 participants completed the questionnaire, of whom 508 (74%) were female. According to IBS diagnostic criteria, only 176 (26%) of participants had IBS. Based on the patient health questionnaire (PHQ) criteria for depression, 497 (72%) of participants were identified as depressed. Similarly, the generalized anxiety disorder (GAD) criteria indicated that 633 (92%) of participants suffered from GAD. The diagnosis of IBS was significantly associated with GAD, depression, and psychological symptoms such as annoyance, irritability, and concern about daily tasks.

Conclusion: There is a significant association between IBS and anxiety and depression, suggesting that psychiatric disorders should be routinely screened for in patients with IBS. Recognizing and treating these comorbidities can improve outcomes for individuals with IBS.