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                            [content] => - Zotepine is an effective second-generation antipsychotic that blocks dopamine (D) and serotonin (5-HT) receptors, but it is linked to higher risks of hyperglycemia and cardiovascular issues. *!  
- The drug inhibits voltage-gated K (Kv) channels in rabbit arterial smooth muscle cells, leading to faster inactivation decay and changes in the inactivation curve, indicating a significant impact on the heart's electrical activity. *!  
- Zotepine's effects on Kv currents are dose-, time-, and use-dependent, predominantly affecting the Kv1.5 subtype, and its inhibition is not altered by some subtype inhibitors but is lessened by the Kv1.5 channel inhibitor DPO-1. *!  
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