Management of endometriosis: a call to multidisciplinary approach.

J Osteopath Med

Department of Medical and Surgical Gynecology, Mayo Clinic, Phoenix, AZ, USA.

Published: December 2024

AI Article Synopsis

  • Endometriosis is characterized by the growth of endometrial-like tissue outside the uterus, classified into three types: superficial, ovarian endometrioma, and deep infiltrating disease, and can affect various areas beyond the pelvis.
  • Diagnosis typically involves a combination of symptom assessment, physical exams, imaging tests, and ultimately requires tissue confirmation for a definitive diagnosis.
  • Treatment options range from medical management focused on symptom relief to surgical interventions, with a preference for excision of lesions and a multidisciplinary approach for more severe cases to enhance long-term outcomes.

Article Abstract

Endometriosis is defined as the presence of endometrial-like glands and stroma outside of the uterus. There are three types of endometriotic lesions: superficial or peritoneal endometriosis, ovarian endometrioma, and deep infiltrating disease. Endometriosis not only occurs in the pelvis but also can be found in extrapelvic sites such as the gastrointestinal tract, upper abdominal viscera, genitourinary tract, abdominal wall, diaphragm, and thoracic cavity. After thorough history and physical examination is performed, imaging, such as ultrasound or magnetic resonance imaging (MRI), should be obtained if there is high suspicion for deep-infiltrating endometriosis to better assess visceral involvement. Endometriosis can be suspected based on symptoms, physical examination findings, and imaging. However, a definitive diagnosis requires histopathologic confirmation. Treatment options include expectant, medical, and surgical management. Endometriosis is largely a quality-of-life issue, and treatment should be tailored accordingly with empiric medical therapy frequently utilized. Medical management focuses on symptom improvement. Surgical management with excision of endometriosis is preferred over ablation or fulguration of endometriotic lesions. In the case of deep or extrapelvic endometriosis, treatment with a multidisciplinary team with experience in the treatment of advanced-stage endometriosis is essential to minimizing morbidity and increasing long-term success.

Download full-text PDF

Source
http://dx.doi.org/10.1515/jom-2024-0105DOI Listing

Publication Analysis

Top Keywords

endometriosis
9
management endometriosis
8
endometriotic lesions
8
physical examination
8
surgical management
8
management
4
endometriosis call
4
call multidisciplinary
4
multidisciplinary approach
4
approach endometriosis
4

Similar Publications

Background: Endometriosis is the most frequent gynecological diseases and accompanied by both physical and psychological symptoms. An increasing number of studies suggested acknowledging endometriosis as a systematic disease due to the multifactorial effects throughout the body. The chronic disease significantly impacts daily life, including romantic relationships.

View Article and Find Full Text PDF

Peritoneal fluid microbiota profile of patients with deep endometriosis.

Microb Pathog

December 2024

Hospital Israelita Albert Einstein, Av. Albert Einstein 627, Morumbi, São Paulo, 05651-901, Brazil; Departamento de Obstetricia e Ginecologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Endometriosis is a chronic gynecological disease that affects 10% of reproductive-aged women and characterized by the presence of endometrial tissue outside the uterus. The disease is linked to a pro-inflammatory environment in the peritoneal fluid of patients, with high levels of cytokines, growth factors, and reactive oxygen species. Changes in the peritoneal fluid, such as altered immune cells and cytokines, can be linked to the immune balance in endometriosis.

View Article and Find Full Text PDF

Implication of the enteric glia in the IBS-like colonic inflammation associated with endometriosis.

BMC Womens Health

December 2024

Department of Basic Sciences - Physiology Division, Ponce Health Sciences University, Ponce Research Institute, PO Box 7004, Ponce, 00732-7004, PR, Puerto Rico.

Background: Endometriosis is a complex gynecological disorder characterized by the ectopic growth of endometrial tissue. Symptoms of endometriosis are known to impair the quality of life of patients, and among these are found dysmenorrhea, chronic pelvic pain, and gastrointestinal (GI) issues. GI issues such as painful bowel movements, bloating and constipation or diarrhea, are one of the common reasons for misdiagnosis with irritable bowel syndrome (IBS).

View Article and Find Full Text PDF

The Microbiome Landscape of Adenomyosis: A Systematic Review.

Reprod Sci

December 2024

Division of Minimally Invasive Gynecologic Surgery, Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville, FL, USA.

Alterations in the microbiome composition have been identified in common gynecologic pathologies such as endometriosis carving a new frontier in diagnosis and treatment. We aimed to examine the existing literature on perturbations in the reproductive tract microbiome of individuals with adenomyosis informing future therapeutic targets. To examine the association between the reproductive tract microbiome composition among individuals with adenomyosis when compared to controls that can lead to new research evaluating novel mechanisms of action and treatment modalities.

View Article and Find Full Text PDF

Endometriosis in later life: an intersectional analysis from the perspective of epistemic injustice.

Med Health Care Philos

December 2024

Center for Interdisciplinary Research on Aging and Care (CIRAC), University of Graz, Schubertstraße 23/I, Graz, 8010, Austria.

Endometriosis, a chronic inflammatory condition affecting 10% of biological women, is widely understudied and particularly overlooked in later life. Discussions surrounding endometriosis predominantly centre on medical gender bias during reproductive years, with limited attention to intersecting factors of discrimination and the impact of ageism on affected individuals. As endometriosis is framed as a disease of reproductive age, research is lacking when it comes to the effects of the illness on the older population.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!