Rhodium-Catalyzed Synthesis of Trifluoromethyl-Containing Allylic Alcohols Via -Alkenyl Transfer with High Stereochemistry Retention.

Herein, we report the rhodium-catalyzed -alkenyl transfer from tertiary allylic alcohols to aryl trifluoromethyl ketones, which provided an efficient way of preparation of trifluoromethyl-containing -allylic alcohols via β--alkenyl elimination. The key -alkenyl-rhodium species were generated with a high degree of stereochemical retention. This reaction featured a broad substrate scope and good functional tolerance and would offer a fascinating approach for the synthesis of -alkenes.