: Osteoarthritis leads to painful joints, disability, restriction of ambulation, and reduces the person's ability to perform activities of daily living. Pain is one of the major symptoms of osteoarthritis. Some patients presented with severe pain while some with severe deformity. : Patients presenting with complaints of knee pain were screened. Written consent was taken from the patient. Radiographic data was collected and these patients were also shown the visual analogue scale (VAS) and asked to rate their pain. Further, the weight-bearing radiographs of both knees of patients in anteroposterior, lateral, and skyline views were also taken. The radiographs were evaluated using the Kellgren-Lawrence classification to determine the grade of osteoarthritis. : For this study, radiographs of 116 patients (48 males (42%), 68 females (58%)) with knee OA who were eligible were included. The prevalence of the disease was highest among patients in the age group 51-60 years. The prevalence of bilateral knee osteoarthritis was observed in 98 patients (86.2%) and that of unilateral in 16 patients (13.8%). The prevalence of associated pain was comparatively higher in females than in males. : This study found there is no significant correlation between VAS pain score and the severity of radiological grading. Hence treatment should be tailored according to symptoms and not just the X-ray findings.
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http://dx.doi.org/10.7759/cureus.73224 | DOI Listing |
In Vitro Cell Dev Biol Anim
December 2024
Laboratorio de Líquido Sinovial, Instituto Nacional de Rehabilitación Luis Guillermo Ibarra Ibarra (INRLGII), Calzada México-Xochimilco No. 289, Col. Arenal de Guadalupe, 14389, Mexico City, Mexico.
Osteoarthritis (OA) is a chronic degenerative disease characterized by the progressive loss of articular cartilage. The role of cigarette smoke (CS) in OA is debated, with some studies suggesting a protective effect while others indicate it may pose a risk. Our preliminary findings suggest a link between smoking in young adults and severe knee OA, though the extent of this contribution is unclear.
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December 2024
Department of Orthopedic Surgery, National Clinical Research Center for Geriatric Disorders, Hunan Engineering Research Center of Biomedical Metal and Ceramic Implants, Xiangya Hospital, Central South University, Changsha, 410008, China.
Osteoarthritis (OA) has been the most common arthritis affecting public health all over the world. Previous experimental research reported that increased low-density lipoprotein cholesterol, along with decreased high-density lipoprotein cholesterol may be associated with increased ectopic bone formation and possible knee OA, while clinical evidence is absent. This study aimed to investigate the association between blood high-density lipoprotein cholesterol (HDL-C) and OA.
View Article and Find Full Text PDFClin Biomech (Bristol)
December 2024
Department of Kinesiology and Applied Physiology, University of Delaware, Newark, DE, USA. Electronic address:
Background: Varus thrust is common in those with knee osteoarthritis. Varus thrust is traditionally identified with visual analysis or motion capture, methods that are either dichotomous or limited to the laboratory setting. Inertial measurement unit data has been found to correlate with motion capture measures of varus thrust in those with severe knee osteoarthritis, allowing for a quantitative and accessible way of measuring varus thrust.
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December 2024
Department of Orthopedic Surgery, The First Hospital of Hebei Medical University, NO. 89 Donggang Road, Shijiazhuang, 063000, Hebei, P. R. China.
The risks and benefits associated with simultaneous bilateral unicompartmental knee arthroplasty (UKA) continue to engender contentious debate. The aim of this study was to compare the clinical outcomes of simultaneous bilateral and unilateral UKA. A retrospective review was performed between 2019 and 2022 on 280 patients (130 simultaneous bilateral vs.
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December 2024
School of Health Sciences, Western Sydney University, Campbelltown, NSW, Australia.
Given the higher fall risk and the fatal sequelae of falls on stairs, it is worthwhile to investigate the mechanism of dynamic balance control in individuals with knee osteoarthritis during stair negotiation. Whole-body angular momentum ([Formula: see text]) is widely used as a surrogate to reflect dynamic balance and failure to constrain [Formula: see text] may increase the fall risk. This study aimed to compare the range of [Formula: see text] between people with and without knee osteoarthritis during stair ascent and descent.
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