Impact of bariatric surgery on infertility in obese women: a systematic review and meta-analysis.

Ann Med Surg (Lond)

Department of General Surgery, School of Medicine, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Published: December 2024

Background: The prevalence of obesity is increasing worldwide, with several consequences, including reduced fertility in both men and women. One of the ways to reduce weight is bariatric surgery. The aim of this systematic review and meta-analysis study was to evaluate the effectiveness of bariatric surgery on weight loss and subsequent improvement of fertility in obese infertile women.

Methods: Several databases were searched using MESH terms to investigate the studies that evaluated the fertility rates after bariatric surgery in infertile obese women. Related data were obtained and analyzed using Stata software with a -value ≤0.05, which was considered as significant.

Results: Of the 283 articles related to the purpose of this study, 9 articles, including 231 obese infertile women, were included in the study. BMI before surgery was 42.2 [95% CI= 39.2-45.2] and BMI after surgery was 31.9 (95% CI= 28.9-34.8), which shows the significance of weight loss after bariatric surgery. Conception rate after bariatric surgery weight loss was increased and was 67% (95% CI= 47-87%, -value <0.05).

Conclusions: Bariatric surgery had a significant effect on the reduction of BMI and subsequent significant improvement of fertility in obese infertile women.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11623841PMC
http://dx.doi.org/10.1097/MS9.0000000000002657DOI Listing

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