AI Article Synopsis
- Lyme disease is a multisystem infection that can impact various parts of the body, including joints and the nervous system, particularly if left untreated.
- A unique case is presented where a patient experienced dysphagia (difficulty swallowing), a symptom not commonly associated with Lyme disease, which usually manifests through neurological issues like facial nerve palsy.
- The increase in Lyme disease cases, especially in certain geographic regions, underscores the importance of early diagnosis and treatment for patients presenting with unusual symptoms like dysphagia.
Article Abstract
Lyme disease is a multisystem infection that can affect the joints, heart, and nervous system when untreated. While it can present with cranial nerve palsy, dysphagia is rarely reported. This case highlights a rare instance of dysphagia in Lyme disease, typically known for neurological symptoms like facial nerve palsy. Despite the absence of erythema migrans or a documented tick bite, the patient's facial palsy, hearing loss, vocal cord paralysis, and dysphagia were attributed to Lyme disease. With the rising prevalence of Lyme disease, similar cases may increase, particularly in endemic regions of North America, Europe, and parts of Asia, emphasizing the need for early diagnosis and treatment in patients with unexplained dysphagia.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11621671 | PMC |
| http://dx.doi.org/10.12786/bn.2024.17.e25 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi.
PLoS Pathog
December 2024
Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America.
Borrelia (or Borreliella) burgdorferi, the causative agent of Lyme disease, is a motile and invasive zoonotic pathogen adept at navigating between its arthropod vector and mammalian host. While motility and chemotaxis are well known to be essential for its enzootic cycle, the role of each methyl-accepting chemotaxis proteins (MCPs) in the infectious cycle of B. burgdorferi remains unclear.
View Article and Find Full Text PDFPlasma Microbial Cell-Free DNA Sequencing for Diagnosis of Pediatric Lyme Disease.
Pediatr Infect Dis J
December 2024
From the Division of Infectious Diseases, Department of Pediatrics, Stony Brook Children's Hospital, Stony Brook, New York.
We conducted an exploratory study of plasma microbial cell-free DNA sequencing for the diagnosis of Lyme disease among pediatric patients. Low levels of Borrelia burgdorferi microbial cell-free DNA (<3-5 molecules per microliter) were observed in 6/9 serologically confirmed participants, including 4/5 with arthritis and 2/3 with multiple erythema migrans.
View Article and Find Full Text PDFThe Tick Microbiome: The "Other Bacterial Players" in Tick Biocontrol.
Microorganisms
November 2024
Department of Entomology, College of Agriculture, Life and Environmental Sciences, University of Arizona, Tucson, AZ 85719, USA.
Hard ticks (family Ixodidae) are one of the most predominant arthropod disease vectors worldwide, second only to mosquitoes. In addition to harboring animal and human pathogens, ticks are known to carry a microbial community constituted of non-pathogenic organisms, which includes maternally inherited intracellular endosymbionts and other environmentally acquired extracellular microorganisms. These microbial communities, which include bacteria, viruses, protozoans, and fungi-with often commensal, mutualistic, or parasitic associations with the tick-comprise the tick microbiome, bacteria being the most studied community.
View Article and Find Full Text PDFSeasonal Dynamics of Ticks and Tick-Borne Pathogens in Republic of Korea.
Pathogens
December 2024
Department of Biomedical Laboratory Science, College of Software and Digital Healthcare Convergence, Yonsei University, Wonju 26493, Republic of Korea.
Tick-borne diseases are a public health problem and a significant burden on the livestock industry. The seasonal abundance of ticks and tick-borne pathogens strongly correlates with the prevalence of these diseases. To investigate the seasonal variation in ticks and tick-borne pathogens, ticks were collected from Gangwon State, Korea, and the tick-borne pathogens , , , and were examined.
View Article and Find Full Text PDFDevelopment, Optimization, and Validation of a Quantitative PCR Assay for Detection in Tick, Wildlife, and Human Samples.
Pathogens
November 2024
Department of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada.
Tick-borne pathogens are growing in importance for human and veterinary research worldwide. We developed, optimized, and validated a reliable quantitative PCR (qPCR; real-time PCR) assay to assess Borrelia burgdorferi infection by targeting two B. burgdorferi genes, and .
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!