Progress in MGJWS: A 74-Year Review of Marcus Gunn Jaw-Winking Syndrome.

J Child Neurol

Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, No.639, Zhizaoju Road, Huangpu District, 200011, Shanghai, China.

Published: December 2024

AI Article Synopsis

  • The text provides a detailed overview of Marcus Gunn jaw-winking syndrome, focusing on its epidemiology, and different possible diagnoses.
  • It explores various causes and mechanisms behind the syndrome, including genetic factors and nerve abnormalities.
  • Additionally, it reviews clinical symptoms, exceptional case presentations, and treatment options, both surgical and nonsurgical, for Marcus Gunn syndrome and related conditions.

Article Abstract

We present an overview of the epidemiology and differential diagnosis of Marcus Gunn jaw-winking syndrome. We scrutinize various hypotheses regarding its etiology and pathogenesis, encompassing abnormal nerve connections, heredity factors, genetic variation, and the release hypothesis, as proposed in prior studies. Furthermore, we discuss the clinical manifestations of Marcus Gunn jaw-winking syndrome and highlight cases with exceptional clinical presentations or concurrent diseases. Moreover, we not only describe the existing surgical and nonsurgical treatments for Marcus Gunn jaw-winking syndrome but also delineate therapies for related conditions such as Meige syndrome, sequelae of facial paralysis, and other oculopalpebral and facial synkinesis. This comprehensive approach serves as a valuable reference for the holistic management of Marcus Gunn jaw-winking syndrome.

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Source
http://dx.doi.org/10.1177/08830738241282698DOI Listing

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