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Spatial co-distribution of tuberculosis prevalence and low BCG vaccination coverage in Ethiopia.
Sci Rep
December 2024
School of Population Health, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia.
While bacille-calmette-guerin (BCG) vaccination is one of the recommended strategies for preventing tuberculosis (TB), its coverage is low in several countries, including Ethiopia. This study investigated the spatial co-distribution and drivers of TB prevalence and low BCG coverage in Ethiopia. This ecological study was conducted using data from a national TB prevalence survey and the Ethiopian demographic and health survey (EDHS) to map the spatial co-distribution of BCG vaccination coverage and TB prevalence.
View Article and Find Full Text PDFMechanisms of breast cancer treatment using Gentiana robusta: evidence from comprehensive bioinformatics investigation.
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December 2024
Department of Clinical Pharmacy, Baoshan Hospital Affiliated to, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
This study investigates the potential treatment of breast cancer utilizing Gentiana robusta King ex Hook. f. (QJ) through an integrated approach involving network pharmacology, molecular docking, and molecular dynamics simulation.
View Article and Find Full Text PDFWeb application using machine learning to predict cardiovascular disease and hypertension in mine workers.
Sci Rep
December 2024
Department of Applied Mathematics, Faculty of Mathematical Science, Ferdowsi University of Mashhad, Mashhad, Iran.
This study presents a web application for predicting cardiovascular disease (CVD) and hypertension (HTN) among mine workers using machine learning (ML) techniques. The dataset, collected from 699 participants at the Gol-Gohar mine in Iran between 2016 and 2020, includes demographic, occupational, lifestyle, and medical information. After preprocessing and feature engineering, the Random Forest algorithm was identified as the best-performing model, achieving 99% accuracy for HTN prediction and 97% for CVD, outperforming other algorithms such as Logistic Regression and Support Vector Machines.
View Article and Find Full Text PDFExploring optimal control strategies in a nonlinear fractional bi-susceptible model for Covid-19 dynamics using Atangana-Baleanu derivative.
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December 2024
Department of Mathematics, GC University, Lahore, Pakistan.
In this article, a nonlinear fractional bi-susceptible [Formula: see text] model is developed to mathematically study the deadly Coronavirus disease (Covid-19), employing the Atangana-Baleanu derivative in Caputo sense (ABC). A more profound comprehension of the system's intricate dynamics using fractional-order derivative is explored as the primary focus of constructing this model. The fundamental properties such as positivity and boundedness, of an epidemic model have been proven, ensuring that the model accurately reflects the realistic behavior of disease spread within a population.
View Article and Find Full Text PDFStrength, durability, and economic analysis of GGBS-based geopolymer concrete with silica fume under harsh conditions.
Sci Rep
December 2024
Civil Engineering Department, Shoolini University, Solan, Himachal Pradesh, 173229, India.
Geopolymer concrete (GPC) offers a sustainable alternative by eliminating the need for cement, thereby reducing carbon dioxide emissions. Using durable concrete helps prevent the corrosion of reinforcing bars and reduces spalling caused by chemical attacks. This study investigates the impact of adding 5, 10, and 15% silica fumes (SF) on the mechanical and durability properties of GPC cured at 60 °C for 24 h.
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