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Precise vesical wall staging of bladder cancer in the era of precision medicine: has it been fulfilled?
Abdom Radiol (NY)
December 2024
Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Urinary bladder cancer is a global disease that poses medical and socioeconomic challenges to patients and healthcare systems. Predicting detrusor invasiveness and pathological grade of bladder cancer by the radiologist is imperative for informed decision-making and effective patient-tailored therapy. Cystoscopy and TURBT are the current gold standard for preoperative histologic diagnosis and local pathological staging but are compromised by their intrusiveness, under-sampling, and staging inaccuracies.
View Article and Find Full Text PDFVI steps to achieve VI-RADS assessment.
Eur J Radiol
December 2024
Department of Internal Medicine, Pathum Thani Hospital, 7 Ladlumkaew Muang district, Pathum Thani 12000, Thailand.
Bladder cancer is categorized into nonmuscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC), distinguished by the presence of detrusor muscle invasion. Urothelial cell carcinoma is the most common subtype of bladder cancer. Transurethral resection of bladder tumor (TURBT) is the standard approach for staging and managing NMIBC, while radical cystectomy remains the cornerstone treatment for MIBC.
View Article and Find Full Text PDFWhy and When Do We Invasively Restage After Neoadjuvant Chemoimmunotherapy?
J Thorac Oncol
December 2024
Scientific Affairs, International Association for the Study of Lung Cancer, Denver, Colorado.
In the Era of Precision Medicine, Is Invasive Mediastinal Restaging Really Not Required Before Lung Resection?
J Thorac Oncol
December 2024
Department of Thoracic Surgery, Hospital Universitari Mútua Terrassa, University of Barcelona, Terrassa, Spain; Network of Centers for Biomedical Research in Respiratory Diseases (CIBERES) Lung Cancer Group, Terrassa, Spain.
Endobronchial ultrasound-guided transbronchial needle aspiration validated with video-assisted mediastinoscopic lymphadenectomy in the mediastinal restaging of patients with stage IIIA non-small cell lung cancer after induction therapy.
Ther Adv Respir Dis
November 2024
Pulmonology Department, Hospital Universitari Mútua Terrassa, University of Barcelona, Plaça Dr Robert 5, Terrassa, Barcelona 08221, Spain.
Article Synopsis
- This study examines the use of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for restaging non-small cell lung cancer (NSCLC) after initial treatment, validated by a separate procedure called video-assisted mediastinoscopic lymphadenectomy (VAMLA).* -
- A retrospective analysis of patients showed that EBUS-TBNA has a moderate sensitivity (63.1%) but excellent specificity (100%) for identifying mediastinal disease, while VAMLA confirmed a 100% accuracy when follow-up was needed after a negative EBUS-TBNA result.* -
- The findings suggest EBUS-TBNA should be the first choice for invasive rest
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