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Histopathological domain adaptation with generative adversarial networks: Bridging the domain gap between thyroid cancer histopathology datasets.
PLoS One
December 2024
Digital Environment Research Institute (DERI), Queen Mary University of London, London, United Kingdom.
Deep learning techniques are increasingly being used to classify medical imaging data with high accuracy. Despite this, due to often limited training data, these models can lack sufficient generalizability to predict unseen test data, produced in different domains, with comparable performance. This study focuses on thyroid histopathology image classification and investigates whether a Generative Adversarial Network [GAN], trained with just 156 patient samples, can produce high quality synthetic images to sufficiently augment training data and improve overall model generalizability.
View Article and Find Full Text PDFNanoscale Systems for Local Activation of Hypoxia-Inducible Factor-1 Alpha: A New Approach in Diabetic Wound Management.
Int J Nanomedicine
December 2024
Department of Pharmaceutics, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa, 11152, Egypt.
Chronic wounds in diabetic patients experience significant clinical challenges due to compromised healing processes. Hypoxia-inducible factor-1 alpha (HIF-1α) is a critical regulator in the cellular response to hypoxia, enhancing angiogenesis and tissue restoration. Nevertheless, the cellular response to the developed chronic hypoxia within diabetes is impaired, likely due to the destabilization of HIF-1α via degradation by prolyl hydroxylase domain (PHD) enzymes.
View Article and Find Full Text PDFMushroom and Kefir Functional Characterizations: Hypolipidemia and Gut Microbiota Modulations in Rat Models.
Food Sci Nutr
December 2024
Nutrition and Food Sciences Department, Faculty of Home Economics Menoufia University Shibin el Kom Egypt.
Article Synopsis
- Hyperlipidemia is linked to poor diet and inactivity, but prebiotics and probiotics, like those found in mushrooms and kefir milk, could help address its effects.
- A study tested dried powdered mushrooms (DPM) and kefir milk (KM) on hyperlipidemic rats, showing significant improvements in health markers such as body weight, blood glucose, and lipid profiles when DPM and KM were included in their diet.
- The findings suggest that the combination of DPM and KM could serve as functional foods to reduce hyperlipidemia and enhance gut health, but further research on humans is necessary.
Comparative Study of Essential Oils Extracted From Miller Seeds Using Hydrodistillation, Steam Distillation, and Superheated Steam Distillation.
Food Sci Nutr
December 2024
Agricultural Extension Directorate, MAAR Damascus Syria.
Miller is a highly valued aromatic and nutritious plant. The unique compositions of its essential oil make it more valuable in the flavor, fragrance, and medicinal industries. However, the potential of superheated steam distillation for obtaining essential oils from its seeds has not been explored in detail.
View Article and Find Full Text PDFDrones and Workers of Honeybee L. Dried Powder: Chemical Composition, Antioxidant, and Anticancer Assessment.
Food Sci Nutr
December 2024
Food Science Department, Faculty of Agriculture Cairo University Giza Egypt.
This study explores honeybee as a food source through chemical analysis of pupa and adult stages of honeybee drones and workers ( L.). The findings reveal that drones exhibited higher protein and fat content, while workers have the highest carbohydrate levels.
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