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Small extracellular vesicles derived from sequential stimulation of canine adipose-derived mesenchymal stem cells enhance anti-inflammatory activity.
BMC Vet Res
January 2025
Center of Excellence for Veterinary Clinical Stem Cells and Bioengineering, Chulalongkorn University, Bangkok, 10330, Thailand.
Background: Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) are recognized for their therapeutic potential in immune modulation and tissue repair, especially in veterinary medicine. This study introduces an innovative sequential stimulation (IVES) technique, involving low-oxygen gas mixture preconditioning using in vitro fertilization gas (IVFG) and direct current electrical stimulation (ES20), to enhance the anti-inflammatory properties of sEVs from canine adipose-derived MSCs (cAD-MSCs). Initial steps involved isolation and comprehensive characterization of cAD-MSCs, including morphology, gene expression, and differentiation potentials, alongside validation of the electrical stimulation protocol.
View Article and Find Full Text PDFEnvironmentally Friendly and Simple Recycling of Titanium Alloy Scrap via Deoxygenation with Hybrid Hydrogen Plasma Arc.
Adv Sci (Weinh)
January 2025
School of Materials Science and Engineering, Harbin Institute of Technology, Harbin, 150001, China.
The potential of hydrogen plasma arc technology for the efficient deoxygenation and recycling of titanium alloy scrap is explored. The results of thermodynamic analysis reveal that hydrogen plasma is suitable for oxygen removal. The intermediate stages of the deoxygenation process are sequentially analyzed, showing that the hydrogen plasma arc primarily facilitated the reduction and dissolution of oxides as well as eliminated interstitial oxygen.
View Article and Find Full Text PDFDevelopment of Father- and Mother-Child Intimacy and Their Association with Internalizing and Externalizing Problems among Early and Middle Chinese Adolescents.
J Youth Adolesc
January 2025
Research Center of Mental Health Education, Southwest University, Chongqing, 400715, China.
Parenting styles and the developmental environment of adolescents in China have undergone significant changes. However, the development of parent-adolescent intimacy among contemporary Chinese adolescents and its impact on internalizing and externalizing problems remain unclear. To address this research gap, this study explored the development of father-child and mother-child intimacy during early and middle adolescence and examined their effects on internalizing and externalizing problems.
View Article and Find Full Text PDFMedical, Endoscopic, and Surgical Treatments for Rectal Cuffitis in IBD Patients with an Ileal Pouch-Anal Anastomosis: A Narrative Review.
Dig Dis Sci
January 2025
Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Background: Ulcerative colitis patients who undergo ileal pouch-anal anastomosis (IPAA) without mucosectomy may develop inflammation of the rectal cuff (cuffitis). Treatment of cuffitis typically includes mesalamine suppositories or corticosteroids, but refractory cuffitis may necessitate advanced therapies or procedural interventions. This review aims to summarize the existing literature regarding treatments options for cuffitis.
View Article and Find Full Text PDFThe Effects of Motivational Interviewing on Promoting Human Papillomavirus Vaccination Initiation and Completion Among South Asian Mother/Daughter Dyads: A Pilot Randomised Controlled Trial.
Int J Behav Med
January 2025
The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong SAR, China.
Background: Vaccination against HPV is an effective strategy for the prevention of HPV infection and cervical cancer. Nevertheless, the HPV vaccine uptake rate is low among ethnic minorities in Hong Kong. This study sought to assess the feasibility and acceptability of motivational interviewing among South Asian mother-daughter dyads and to preliminarily examine its effects on knowledge of HPV infection and vaccination, health beliefs, intention to have the daughters vaccinated, and initiation and completion of HPV vaccine series.
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