Management strategies and oncological follow-up of a bicentric French cohort of biopsied renal oncocytomas.

Objective: Renal oncocytoma is a benign renal tumour whose management remains heterogeneous and poorly codified. The aim of this study was to describe the management strategies and evolution of a cohort of biopsied renal oncocytomas.

Materials And Methods: We retrospectively reviewed renal oncocytomas biopsied in 2 French academic centres between 2009 and 2016. Demographic, anatomopathological, radiological and operative (if operated) variables were collected and compared between patients operated on and those monitored in order to identify those associated with the management strategy and clinical course.

Results: Fifty-three patients were included with a mean follow-up of 29.6±32.3 months. Patients operated on immediately were younger (mean 57±11.5 years vs 68±9.8 years; P=0.007), less comorbid (Charlson 2.8 vs 4; P=0.01) with a higher RENAL score (9 vs 6; P<0.001) and a larger tumour size (mean 58±27 vs 27±13mm; P=0.002). Of the 28 patients monitored, 23 (82%) were still being monitored at the end of the study. The median duration of monitoring was 17.56 months. For the cohort as a whole, the mean tumour growth rate was 2.6mm/year (±2.5).

Conclusion: The management of oncytomas was heterogeneous. Tumour size, patient age and his comorbidities, RENAL score and tumour growth rate were the criteria associated with surgical treatment.