The regulatory mechanisms of silencers have remained poorly understood. In this issue, Hofbauer et al. conduct a genome-wide screen in Drosophila melanogaster and reveal three silencer types that appear to work alone-without the need for combinatorial action, traditional chromatin marks, or open chromatin regions.
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| http://dx.doi.org/10.1016/j.molcel.2024.11.005 | DOI Listing |
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The experiences of organizational silence among nurses: a qualitative meta-synthesis.
BMC Nurs
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Nursing Department, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, 200072, China.
Objective: A growing body of research shows that the organizational silence among nurses not only affects their job satisfaction and performance but also exacerbates their intention to leave their jobs, posing a threat to the long-term stability of the nursing team. Therefore, the aim of this study was to synthesize existing qualitative research to explore the real experiences of nurses' organizational silence behavior and gain insight into the motivations and feelings behind it.
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Biol Open
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Institut Curie, Université PSL, CNRS UMR3348, 91400 Orsay, France.
The SUMO-targeted ubiquitin ligase (STUbL) family is involved in multiple cellular processes via a wide range of mechanisms to maintain genome stability. One of the evolutionarily conserved functions of STUbL is to promote changes in the nuclear positioning of DNA lesions, targeting them to the nuclear periphery. In Schizossacharomyces pombe, the STUbL Slx8 is a regulator of SUMOylated proteins and promotes replication stress tolerance by counteracting the toxicity of SUMO conjugates.
View Article and Find Full Text PDFThe power of music: impact on EEG signals.
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Department of Neurology and Clinical Neurophysiology Unit, Faculty of Medicine-Cairo University, Cairo, Egypt.
Article Synopsis
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TelAP2 links TelAP1 to the telomere complex in Trypanosoma brucei.
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Quantitative Proteomics, Institute of Molecular Biology (IMB), 55128, Mainz, Germany.
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