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Is the DNP Appropriate for the Nurse Educator?
J Nurs Educ
December 2024
Rush University College of Nursing, Chicago, Illinois.
Perioperative Nursing Management of Patients With Rheumatoid Arthritis Undergoing Total Joint Arthroplasty.
Orthop Nurs
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Eileen Campbell, APRN, EdD, ACNS-BC, CNS-CP, CNOR, Department of Nursing, Western Connecticut State University, Danbury, CT.
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that causes joint inflammation, pain, and potential disability. Patients with RA have unique needs when undergoing total joint arthroplasty (TJA). Careful and comprehensive evaluation and management includes physical assessment, patient history, and knowledge about the medication regimen in the setting of elective TJA.
View Article and Find Full Text PDFInvestigation of Protein Therapeutics in Frozen Conditions Using DNP MAS NMR: A Study on Pembrolizumab.
Mol Pharm
December 2024
Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
Article Synopsis
- * This study specifically investigates the high-concentration monoclonal antibody pembrolizumab (Keytruda) and its behavior in frozen solutions using advanced techniques like dynamic nuclear polarization (DNP) and solid-state NMR (ssNMR).
- * Findings reveal how these methods allow detailed analysis of the protein's structure, dynamics, and the behavior of its excipients at low temperatures, highlighting their potential for improving the stability assessment of biological drugs in frozen conditions.
DNA tetrahedron nanoparticles service as a help carrier and adjvant of mRNA vaccine.
J Transl Med
November 2024
Department of Stomatology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
Aim Of The Study: To investigate the potential of DNA nanoparticles (DNPs) as carriers and adjuvants for mRNA vaccines.
Materials And Methods: Customized oligonucleotides were assembled into DNA tetrahedra (DNA-TH), which were subsequently complexed with streptavidin and mRNA encoding green fluorescent protein (GFP). Various assays were conducted to evaluat the stability of the DNPs, their cellular uptake, immune activation potential, and GFP mRNA transcription efficiency.
Identifying Professional Goals and Promoting Career Development in Nursing Students Through Reflection and Simulation.
Nurs Educ Perspect
September 2024
About the Authors The authors are affiliated with Stony Brook University, Stony Brook, New York. Santina Abbate, PhD, MPA, RN, NE-BC, is clinical assistant professor and coordinator, Stony Brook Nursing Student Internship Program, Stony Brook University School of Nursing. Kathleen M. Gambino, EdD, RN, is clinical associate professor and program director, Registered Nurse to Baccalaureate Program and Registered Nurse to Master's Program, Stony Brook University School of Nursing. Paula M. Timoney, DNP, APRN, NNP-BC, is clinical associate professor and chair, Graduate Studies in Nursing Organization and Leadership, and director, Master's in Nursing Leadership Program and Neonatal Nurse Practitioner Programs, Stony Brook University School of Nursing. Anna-Marie Wellins, DNP, MEd, ANP-C, is clinical associate professor and director, Master of Nursing Education Program, Stony Brook University School of Nursing. Marianna Savoca, PhD, is associate vice president for career readiness & experiential education, Career Center, and research associate professor, School of Professional Development, Stony Brook University Melville Library. Urszula Zalewski, MBA, MS, is director of experiential education, Career Center, Stony Brook University Melville Library. For more information, contact Dr. Gambino at
Career planning is an important but often neglected component of a nursing program curriculum. To increase retention and encourage professional advancement at the school of nursing of a large, public university in the Northeast, a virtual simulated career development day was established to provide students with the tools needed to navigate the job acquisition process and secure appropriate employment. Course outcomes and student feedback indicated that a successful transition to practice and advancement to higher levels of professional nursing can be promoted through the development of superior interviewing skills, a strong resume, and insight regarding one's professional goals and values.
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