AI Article Synopsis
- The study examines how different access protocols to palatable food (PF) influence binge-like eating behaviors in adolescent male Wistar rats, which may be relevant for understanding human obesity.
- Three groups of rats were given varying access to PF—continuous, intermittent, and weekend access—over a period of six weeks, followed by a withdrawal period.
- Results showed that restricted access led to increased binge-like eating, with the intermittent access group exhibiting the highest levels of binge eating, highlighting how food availability affects consumption patterns during adolescence.
Article Abstract
Introduction: Consumption of palatable food (PF) can lead to chronic overconsumption and obesity. Furthermore, adolescents may be vulnerable to excessively reinforcing foods, which increases the probability of developing overweight and obesity in adulthood. The role of PF availability in binge-like intake among adolescents without caloric needs remains unclear. The present study aimed to evaluate which PF access protocol is the most sensitive to induce increased caloric intake and binge-like eating during adolescence.
Methods: We used 24 male Wistar rats [30 postnatal days (PND)]; standard food and water were provided . Rats were randomly assigned to one of three groups: (a) continuous, daily access to PF; (b) intermittent, 1-day access/1-day no-access; or (c) weekend, 3 days-access/4 days no-access. All groups had 1 h access to PF (chocolate sandwich cookies). Access protocols were maintained for 6 weeks; afterward, rats underwent a 7-day withdrawal period, and were then evaluated on a binge-eating test.
Results: Chronic restricted PF access induces binge-like intake, with intermittent access resulting in the highest binge index. Additionally, caloric intake of PF increases over time during adolescence, with differential effects of intermittent and weekend access.
Conclusion: Chronic restricted access to PF during adolescence induces binge-like intake, with differences depending on PF availability. This can lead to chronic overconsumption under non-homeostatic conditions.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11617159 | PMC |
| http://dx.doi.org/10.3389/fpsyg.2024.1468984 | DOI Listing |
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